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Collaboration and License Agreements - Amgen, Inc - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended
Mar. 31, 2017
$ / shares
shares
Nov. 18, 2016
USD ($)
Sep. 28, 2016
USD ($)
Agreement
Nov. 30, 2016
USD ($)
Sep. 30, 2016
USD ($)
Mar. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2016
USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Proceeds from the issuance of common stock             $ 12,691,937 $ 25,544
Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Stock issued, price per share | $ / shares $ 7.16         $ 7.16 $ 7.16  
Collaboration and License agreements | Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Agreement date Sep. 28, 2016              
Number of agreements | Agreement     2          
ARO-AMG1 Agreement | Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Additional amount of common stock shares agreed to sell upon exercise of option     $ 5,000,000          
Number of trading days, used to calculate share price of Common Stock, surrounding option exercise date     30 days          
Cash received as due under collaboration agreement         $ 5,000,000      
Deferred revenue         $ 5,000,000      
Deferred revenue amortized into revenue           $ 600,000 $ 1,300,000  
Collaboration and License agreements                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Cash received as due under collaboration agreement     $ 35,000,000          
Collaboration and License agreements | Maximum                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Option payments, and development, regulatory and sales milestone payments.     617,000,000          
Collaboration and License agreements | Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Proceeds from the issuance of common stock     $ 21,500,000          
ARO-LPA Agreement | Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Cash received as due under collaboration agreement       $ 30,000,000        
Deferred revenue       $ 30,000,000        
Deferred revenue amortized into revenue           7,800,000 11,500,000  
Revenue generated from work orders under services agreement           $ 600,000 $ 600,000  
Common Stock Purchase Agreement | Amgen                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Agreement date Sep. 28, 2016              
Shares issued | shares 3,002,793         3,002,793 3,002,793  
Stock issued, price per share | $ / shares $ 7.16         $ 7.16 $ 7.16  
Proceeds from the issuance of common stock   $ 12,500,000            
Common Stock Purchase Agreement | Amgen | NASDAQ                
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Number of trading days, used to calculate weighted average price of Common Stock, listed in stock market 30 days