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v3.10.0.1

Consolidated Statement of Stockholders' Equity - USD ($) | Total | Common stock issued for cash at $5.90 per share | Amgen | Preferred Stock | Common Stock | Common Stock Common stock issued for cash at $5.90 per share | Common Stock Amgen | Additional Paid-In Capital | Additional Paid-In Capital Common stock issued for cash at $5.90 per share | Additional Paid-In Capital Amgen | Accumulated Other Comprehensive Income (loss) | Accumulated Deficit | Non-controlling Interest
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning Balance, Amount at Sep. 30, 2015 | $ 109,621,634 |  |  | $ 16 | $ 151,914 |  |  | $ 426,873,358 |  |  | $ (136,425) | $ (316,712,041) | $ (555,188)
Beginning Balance, Shares at Sep. 30, 2015 |  |  |  | 15,652 | 59,544,677 |  |  |  |  |  |  |  |
Exercise of warrants, Amount | 3,691,398 |  |  |  | $ 853 |  |  | 3,690,545 |  |  |  |  |
Exercise of warrants, Shares |  |  |  |  | 852,532 |  |  |  |  |  |  |  |
Exercise of stock options, Amount | 133,869 |  |  |  | $ 37 |  |  | 133,832 |  |  |  |  |
Exercise of stock options, Shares |  |  |  |  | 37,187 |  |  |  |  |  |  |  |
Stock-based compensation | 11,595,816 |  |  |  |  |  |  | 11,595,816 |  |  |  |  |
Common stock- Restricted Stock Units vesting, Amount | (670,765) |  |  |  | $ 428 |  |  | (671,193) |  |  |  |  |
Common stock- Restricted Stock Units vesting, Shares |  |  |  |  | 428,187 |  |  |  |  |  |  |  |
Stock issuances |  | $ 43,231,435 | $ 9,000,000 |  |  | $ 7,627 | $ 1,257 |  | $ 43,223,808 | $ 8,998,743 |  |  |
Stock issuances, Shares |  |  |  |  |  | 7,627,119 | 1,256,983 |  |  |  |  |  |
Foreign currency translation adjustments | 143,874 |  |  |  |  |  |  |  |  |  | 143,874 |  |
Net loss | (81,723,002) |  |  |  |  |  |  |  |  |  |  | (81,723,002) |
Ending Balance, Amount at Sep. 30, 2016 | 95,024,259 |  |  | $ 16 | $ 162,116 |  |  | 493,844,909 |  |  | 7,449 | (398,435,043) | (555,188)
Ending Balance, Shares at Sep. 30, 2016 |  |  |  | 15,652 | 69,746,685 |  |  |  |  |  |  |  |
Exercise of stock options, Amount | 271,931 |  |  |  | $ 136 |  |  | 271,795 |  |  |  |  |
Exercise of stock options, Shares |  |  |  |  | 135,730 |  |  |  |  |  |  |  |
Stock-based compensation | 7,891,595 |  |  |  |  |  |  | 7,891,595 |  |  |  |  |
Common stock- Restricted Stock Units vesting, Amount | (403,261) |  |  |  | $ 481 |  |  | (403,742) |  |  |  |  |
Common stock- Restricted Stock Units vesting, Shares |  |  |  |  | 481,212 |  |  |  |  |  |  |  |
Stock issuances |  |  | $ 12,420,000 |  |  |  | $ 1,746 |  |  | $ 12,418,254 |  |  |
Stock issuances, Shares |  |  |  |  |  |  | 1,745,810 |  |  |  |  |  |
Preferred stock converted to common stock, Amount |  |  |  | $ (16) | $ 2,671 |  |  | (2,655) |  |  |  |  |
Preferred stock converted to common stock, Shares |  |  |  | (15,652) | 2,670,989 |  |  |  |  |  |  |  |
Exercise of exchange rights, Amount | 17,150 |  |  |  | $ 5 |  |  | 17,145 |  |  |  |  |
Exercise of exchange rights, Shares |  |  |  |  | 5,000 |  |  |  |  |  |  |  |
Foreign currency translation adjustments | 25,783 |  |  |  |  |  |  |  |  |  | 25,783 |  |
Net loss | (34,380,295) |  |  |  |  |  |  |  |  |  |  | (34,380,295) |
Ending Balance, Amount at Sep. 30, 2017 | 80,867,162 |  |  |  | $ 167,155 |  |  | 514,037,301 |  |  | 33,232 | (432,815,338) | (555,188)
Ending Balance, Shares at Sep. 30, 2017 |  |  |  |  | 74,785,426 |  |  |  |  |  |  |  |
Exercise of warrants, Amount | 1,237,429 |  |  |  | $ 288 |  |  | 1,237,141 |  |  |  |  |
Exercise of warrants, Shares |  |  |  |  | 288,473 |  |  |  |  |  |  |  |
Exercise of stock options, Amount | $ 2,656,710 |  |  |  | $ 605 |  |  | 2,656,105 |  |  |  |  |
Exercise of stock options, Shares | 604,611 |  |  |  | 604,611 |  |  |  |  |  |  |  |
Stock-based compensation | $ 8,454,607 |  |  |  |  |  |  | 8,454,607 |  |  |  |  |
Common stock- Restricted Stock Units vesting, Amount | (54,668) |  |  |  | $ 1,327 |  |  | (55,995) |  |  |  |  |
Common stock- Restricted Stock Units vesting, Shares |  |  |  |  | 1,326,792 |  |  |  |  |  |  |  |
Stock issuances | 56,585,035 |  |  |  | $ 11,500 |  |  | 56,573,535 |  |  |  |  |
Stock issuances, Shares |  |  |  |  | 11,500,000 |  |  |  |  |  |  |  |
Foreign currency translation adjustments | (54,796) |  |  |  |  |  |  |  |  |  | (54,796) |  |
Net loss | (54,450,478) |  |  |  |  |  |  |  |  |  |  | (54,450,478) |
Ending Balance, Amount at Sep. 30, 2018 | $ 95,241,001 |  |  |  | $ 180,875 |  |  | $ 582,902,694 |  |  | $ (21,564) | $ (487,265,816) | $ (555,188)
Ending Balance, Shares at Sep. 30, 2018 |  |  |  |  | 88,505,302 |  |  |  |  |  |  |  |

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