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Collaboration and License Agreements - Janssen Pharmaceuticals, Inc - Additional Information (Detail) |  | 1 Months Ended | 3 Months Ended
--- | --- | --- | ---
Oct. 03, 2018 USD ($) Obligation | Oct. 31, 2018 USD ($) Target $ / shares shares | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Proceeds from the issuance of common stock |  |  | $ 60,521,729 |
Revenues |  |  | 34,657,896 | $ 3,509,821
Collaboration and License agreements |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Initial transaction price | $ 197,800,000 |  |  |
JJDC | Common Stock Purchase Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Shares issued | shares |  | 3,260,869 |  |
Stock issued, price per share | $ / shares |  | $ 23.00 |  |
Janssen and JJDC |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Revenues |  |  | 34,700,000 |
Contract assets |  |  | 3,200,000 |
Contract liabilities |  |  | $ 158,100,000 |
Janssen and JJDC | Common Stock Purchase Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Shares issued | shares |  | 3,260,869 |  |
Stock issued, price per share | $ / shares |  | $ 23.00 |  |
Proceeds from the issuance of common stock |  | $ 75,000,000 |  |
Janssen and JJDC | Collaboration and License agreements |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Proceeds from the issuance of common stock |  | 75,000,000 |  |
Cash received as due under collaboration agreement |  | 175,000,000 |  |
Janssen |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Number of distinct performance obligations | Obligation | 1 |  |  |
Janssen | Common Stock Purchase Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Janssen | License Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Janssen | License Agreement | Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development, regulatory and sales milestones payments |  | $ 1,600,000,000 |  |
Janssen | Research Collaboration and Option Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Number of additional targets for development, regulatory and sales milestone payments | Target |  | 3 |  |
Janssen | Collaboration Agreement | Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development, regulatory and sales milestones payments |  | $ 1,900,000,000 |  |

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