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Collaboration and License Agreements - Horizon Therapeutics Ireland DAC - Additional Information (Detail) - Horizon Therapeutics Ireland DAC $ in Millions | Jun. 18, 2021 USD ($) Obligation | Oct. 07, 2020 Obligation Bundle | Jul. 31, 2021 USD ($)
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ARO-XDH |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Agreement date | Jun. 18, 2021 |  |
Number of distinct performance obligations | Obligation | 1 |  |
Initial transaction price | $ 40.0 |  |
ARO-XDH | Subsequent Event |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Cash received as due under collaboration agreement |  |  | $ 40.0
License Agreement |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Number of distinct bundle | Bundle |  | 1 |
Number of distinct performance obligations | Obligation |  | 1 |
Maximum | ARO-XDH |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Development regulatory and sales milestones payments | $ 660.0 |  |

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