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v3.22.2.2

Organization and Significant Accounting Policies (Details) - USD ($) |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Apr. 25, 2022 | Apr. 30, 2022 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2019
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Cash, cash equivalents and restricted cash |  |  | $ 108,005,000 | $ 184,434,000 | $ 143,583,000 | $ 221,804,000
Restricted cash |  |  | 7,300,000 | 2,400,000 |  |
Short-term investments |  |  | 268,391,000 | 56,627,000 |  |
Long-term investments |  |  | 105,872,000 | 245,595,000 |  |
Net increase (decrease) in cash and investments |  |  | 131,100,000 |  |  |
Proceeds from upfront capital |  |  | 60,000,000 | 0 | $ 0 |
Proceeds from sale of marketable debt securities |  | $ 122,300,000 |  |  |  |
Intangible assets subject to amortization, impairment |  |  | 0 | 0 |  |
Fair value of contingent consideration obligation due to discontinuation of clinical trials |  |  | $ 0 | $ 0 |  |
Minimum |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Property and equipment, useful life |  |  | 3 years |  |  |
Maximum |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Amount insured in FDIC per account |  |  | $ 250,000 |  |  |
Property and equipment, useful life |  |  | 7 years |  |  |
Visirna Therapeutics, Inc. | Variable Interest Entity, Primary Beneficiary |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Proceeds from upfront capital | $ 60,000,000 |  | $ 60,000,000 |  |  |
GSK |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Upfront milestone payment received |  |  | 120,000,000 |  |  |
Janssen |  |  |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |  |  |
Development regulatory and sales milestones payments |  |  | $ 4,900,000,000 |  |  |

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