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Collaboration and License Agreements - Glaxosmithkline Intellectual Property (No. 3) Limited - Additional Information (Detail) |  |  | 3 Months Ended |  |
--- | --- | --- | --- | --- | ---
Nov. 22, 2021 USD ($) Obligation Bundle | Oct. 03, 2018 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Jan. 31, 2022 USD ($) | Sep. 30, 2021 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Revenues |  |  | $ 27,439,000 | $ 21,303,000 |  |
Contract liabilities |  |  | $ 108,652,000 |  |  | $ 111,055,000
Collaboration and License agreements |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Initial transaction price |  | $ 252,700,000 |  |  |  |
Collaboration and License agreements | GSK |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Milestone payment | $ 120,000 |  |  |  |  |
Milestone payment receivable at start of phase two | 30,000 |  |  |  |  |
Milestone payment receivable upon achievement of phase two and first patient dosed in phase three | $ 100,000 |  |  |  |  |
Tiered royalties on net product sales receive description | The Company is further eligible to receive tiered royalties on net product sales in a range of mid-teens to twenty percent. |  |  |  |  |
Collaboration and License agreements | Maximum | GSK |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Commercial milestone payments at first commercial sale | $ 190,000 |  |  |  |  |
Sales-related milestone payments | $ 590,000 |  |  |  |  |
ARO-HSD Agreement | GSK |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Number of distinct bundle | Bundle | 1 |  |  |  |  |
Number of distinct performance obligations | Obligation | 1 |  |  |  |  |
Initial transaction price | $ 120,000,000.0 |  |  |  |  |
Revenues | 0 |  |  |  |  |
Contract assets | 0 |  |  |  |  |
Contract liabilities | $ 0 |  |  |  |  |
ARO-HSD Agreement | GSK | Subsequent Event |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Cash received as due under collaboration agreement |  |  |  |  | $ 120,000,000.0 |

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