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Collaboration and License Agreements - Janssen Pharmaceuticals, Inc - Additional Information (Detail) |  | 3 Months Ended |
--- | --- | --- | ---
Oct. 03, 2018 USD ($) Target Obligation | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Sep. 30, 2021 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Revenues |  | $ 27,439,000 | $ 21,303,000 |
Deferred revenue |  | 108,652,000 |  | $ 111,055,000
Collaboration and License agreements |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Initial transaction price | $ 252,700,000 |  |  |
JJDC | Common Stock Purchase Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Proceeds from the issuance of common stock | $ 75,000,000.0 |  |  |
Janssen | Collaboration and License agreements |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Cash received as due under collaboration agreement | 175,000,000.0 |  |  |
Janssen |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development, regulatory and sales milestones payments |  | 6,200,000,000 |  |
Milestone payment | $ 70,000,000.0 |  |  |
Janssen | License Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Janssen | License Agreement | Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development, regulatory and sales milestones payments | $ 1,600,000,000 |  |  |
Janssen | Research Collaboration and Option Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Agreement date | Oct. 03, 2018 |  |  |
Number of additional targets for development, regulatory and sales milestone payments | Target | 3 |  |  |
Janssen | Collaboration Agreement | Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development, regulatory and sales milestones payments | $ 1,900,000,000 |  |  |
Janssen | JNJ-3989 (ARO-HBV) Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Milestone payment | $ 25,000,000.0 |  |  |
Number of distinct performance obligations | Obligation | 1 |  |  |
Revenues |  | 0 | 12,700,000 |
Contract assets |  | 0 |  |
Deferred revenue |  | 0 |  |
Janssen | JNJ-75220795 (ARO-JNJ1) |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Revenues |  | 0 | $ 300,000 |
Contract assets |  | 0 |  |
Deferred revenue |  | $ 0 |  |

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