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Organization and Significant Accounting Policies - Additional Information (Detail) $ in Thousands |  | 6 Months Ended |  |
--- | --- | --- | --- | ---
Dec. 20, 2021 ft² a | Mar. 31, 2022 USD ($) | Nov. 19, 2021 ft² | Sep. 30, 2021 USD ($)
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Cash and cash equivalents |  | $ 86,408 |  | $ 184,434
Restricted Cash |  | 7,900 |  |
Short-term investments |  | 192,912 |  | 56,627
Marketable securities |  | 122,600 |  |
Long-term investments |  | 201,590 |  | $ 245,595
Net increase (decrease) in cash and investments |  | 9,900 |  |
GSK |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Upfront milestone payment received |  | 120,000 |  |
Janssen |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Development regulatory and sales milestones payments |  | $ 4,900,000 |  |
Wisconsin | Drug Manufacturing Facility |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Planned area of the site | ft² | 140,000 |  |  |
Wisconsin | Laboratory and Office Facility |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Planned area of the site | ft² | 115,000 |  |  |
Wisconsin | Verona Technology Park |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Land purchased, number of acres | a | 13 |  |  |
California | Research Facility in San Diego |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Office space leases, in square feet | ft² |  |  | 144,000 |

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