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Collaboration and License Agreements - Takeda Pharmaceuticals U.S.A., Inc - Additional Information (Detail) $ in Thousands |  | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | --- | ---
Oct. 07, 2020 USD ($) bundle obligation | Jun. 30, 2022 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2022 USD ($) | Jun. 30, 2021 USD ($) | Sep. 30, 2021 USD ($) | Jan. 31, 2021 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Revenues |  | $ 32,412 | $ 45,891 | $ 211,656 | $ 100,004 |  |
Deferred revenue |  | 84,288 |  | 84,288 |  | $ 111,055 |
Deferred revenue, net of current portion |  | 71,162 |  | 71,162 |  | $ 131,495 |
Takeda License Agreement | License and Co-Funding Agreement |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Cash received as due under collaboration agreement |  |  |  |  |  |  | $ 300,000
Number of distinct performance obligations | obligation | 1 |  |  |  |  |  |
Number of distinct bundle | bundle | 1 |  |  |  |  |  |
Initial transaction price | $ 300,000 |  |  |  |  |  |
Revenues |  | 25,500 | $ 35,700 | 67,100 | $ 69,300 |  |
Contract assets |  | 0 |  | 0 |  |  |
Takeda License Agreement | License and Co-Funding Agreement | Deferred Revenue |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  | 71,000 |  | 71,000 |  |  |
Deferred revenue, net of current portion |  | 71,200 |  | 71,200 |  |  |
Takeda License Agreement | License and Co-Funding Agreement | Accrued Expenses |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  | $ 7,800 |  | $ 7,800 |  |  |
Takeda License Agreement | License and Co-Funding Agreement | Minimum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 20.00% |  |  |  |  |  |
Takeda License Agreement | License and Co-Funding Agreement | Maximum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 25.00% |  |  |  |  |  |
Development regulatory and sales milestones payments |  |  |  |  |  |  | $ 740,000

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