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Organization and Significant Accounting Policies - Additional Information (Detail) ft² in Thousands, $ in Thousands |  | 9 Months Ended |  |
--- | --- | --- | --- | ---
Dec. 20, 2021 ft² a | Jun. 30, 2022 USD ($) ft² a | Nov. 19, 2021 ft² | Sep. 30, 2021 USD ($)
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Tax increment financing award |  | $ 16,000 |  |
State income tax credits |  | 2,500 |  |
Cash and cash equivalents |  | 139,439 |  | $ 184,434
Restricted cash |  | 7,400 |  |
Short term investments |  | 277,057 |  | 56,627
Marketable securities |  | 0 |  | 126,728
Long term investments |  | 165,920 |  | $ 245,595
Decrease in cash and investments |  | 31,000 |  |
GSK |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Upfront milestone payment received |  | 120,000 |  |
Janssen |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Development regulatory and sales milestones payments |  | 4,900,000 |  |
Variable Interest Entity, Primary Beneficiary | Visirna Therapeutics, Inc. |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Cash and cash equivalents |  | $ 60,000 |  |
Wisconsin | Verona Technology Park |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Land purchased, number of acres | a | 13 | 13 |  |
Wisconsin | Drug Manufacturing Facility |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Planned area of the site (in sq ft) | ft² | 160 | 160 |  |
Wisconsin | Laboratory and Office Facility |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Planned area of the site (in sq ft) | ft² | 140 | 140 |  |
California | Research Facility in San Diego |  |  |  |
Organization And Significant Accounting Policies [Line Items] |  |  |  |
Office space leases (in sq ft) | ft² |  | 144 | 144 |

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