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Collaboration and License Agreements - Joint Venture and License Agreement with Visirna Therapeutics, Inc. (Details) - USD ($) $ in Thousands |  | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Apr. 25, 2022 | Mar. 31, 2023 | Mar. 31, 2022 | Mar. 31, 2023 | Mar. 31, 2022 | Sep. 30, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Proceeds from the sale of future royalties |  |  |  | $ 250,000 | $ 0 |
Revenue |  | $ 146,267 | $ 151,805 | 208,813 | $ 179,244 |
Deferred revenue |  | 29,839 |  | 29,839 |  | $ 74,099
Visirna Therapeutics, Inc. | Visirna License Agreement |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Revenue |  |  |  | 900 |  |
Contract assets |  | 0 |  | 0 |  |
Deferred revenue |  | $ 0 |  | $ 0 |  |
Visirna Therapeutics, Inc. | Visirna License Agreement | Variable Interest Entity, Primary Beneficiary |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Proceeds from the sale of future royalties | $ 60,000 |  |  |  |  |

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