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Collaboration and License Agreements - Takeda Pharmaceutical Company Limited (Details) $ / shares in Units, $ in Thousands |  | 3 Months Ended | 6 Months Ended |  |
--- | --- | --- | --- | --- | ---
Oct. 07, 2020 USD ($) obligation bundle | Mar. 31, 2023 USD ($) $ / shares | Mar. 31, 2022 USD ($) $ / shares | Mar. 31, 2023 USD ($) $ / shares | Mar. 31, 2022 USD ($) $ / shares | Sep. 30, 2022 USD ($) | Jan. 31, 2021 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Development regulatory and sales milestones payments |  | $ 3,600,000 |  | $ 3,600,000 |  |  |
Revenues |  | $ 146,267 | $ 151,805 | $ 208,813 | $ 179,244 |  |
Diluted (in dollars per share) | $ / shares |  | $ 0.45 | $ 0.41 | $ 0.07 | $ (0.18) |  |
Deferred revenue, net of current portion |  | $ 1,075 |  | $ 1,075 |  | $ 55,950 |
Deferred revenue |  | 29,839 |  | 29,839 |  | $ 74,099 |
Takeda | License and Co-Funding Agreement |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Cash received as due under collaboration agreement |  |  |  |  |  |  | $ 300,000
Milestone payment |  | 40,000 |  | 40,000 |  |  |
Number of distinct performance obligations | obligation | 1 |  |  |  |  |  |
Number of distinct bundle | bundle | 1 |  |  |  |  |  |
Initial transaction price | $ 300,000 |  |  |  |  |  |
Revenues |  | $ 61,400 |  | $ 61,400 |  |  |
Diluted (in dollars per share) | $ / shares |  | $ 0.57 |  | $ 0.57 |  |  |
Milestone payment receivable |  | $ 40,000 |  | $ 40,000 |  |  |
Takeda | License and Co-Funding Agreement | Deferred Revenue |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue, net of current portion |  | 30,900 |  | 30,900 |  |  |
Deferred revenue |  | 29,800 |  | 29,800 |  |  |
Takeda | License and Co-Funding Agreement | Accrued Expenses |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  | 9,400 |  | 9,400 |  |  |
Takeda | License and Co-Funding Agreement | Minimum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 20.00% |  |  |  |  |  |
Takeda | License and Co-Funding Agreement | Maximum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 25.00% |  |  |  |  |  |
Development regulatory and sales milestones payments |  | $ 527,500 |  | $ 527,500 |  |  |

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