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Stock-Based Compensation (Tables)

12 Months Ended

Sep. 30, 2024

Share-Based Payment Arrangement [Abstract]

Summary of Awards Outstanding

The following table presents a summary of awards outstanding:

			As of September 30, 2024
						2013 Plan						2021 Plan						Inducement Awards						Total
Granted and outstanding awards:
Options						1,290,720						32,151						655,645						1,978,516
Restricted stock units						1,608,510						2,768,776						536,026						4,913,312
Total						2,899,230						2,800,927						1,191,671						6,891,828

Schedule of Share-Based Payment Arrangement, Expensed

The following table summarizes stock-based compensation expenses included in operating expenses:

						Year Ended September 30,
						2024						2023						2022
						(in thousands)
Research and development						$	29,527					$	34,332					$	32,371
General and administrative						37,570						43,798						88,522
Total						$	67,097					$	78,130					$	120,893

Summarized Information about Stock Options

The following table presents a summary of the stock option activity for the year ended September 30, 2024:

			Shares						Weighted- Average Exercise Price Per Share						Weighted- Average Remaining Contractual Term (Years)						Aggregate Intrinsic Value
Outstanding at September 30, 2023			2,263,477						$	22.68
Granted			—						—
Cancelled or expired			(58,957)						36.80
Exercised			(226,004)						10.64
Outstanding at September 30, 2024			1,978,516						$	23.39					3.5						$	13,782,840
Exercisable at September 30, 2024			1,975,824						$	23.33					3.5						$	13,782,840

Assumptions Used to Value Stock Options

The following table provides the assumptions used in the calculation of grant-date fair values of these stock options based on the Black-Scholes option pricing model:

			Year Ended September 30,
			2024(5)						2023						2022(5)
Expected dividend yield(1)			—						—						—
Risk-free interest rate(2)			N/A						3.69 – 4.57%						N/A
Expected volatility(3)			N/A						86.4		%				N/A
Expected term (in years)(4)			N/A						6.25						N/A
Weighted-average grant date fair value per share			N/A						25.61						N/A

(1) The dividend yield is zero as the Company currently does not pay a dividend.

(2) The risk-free interest rate is based on that of the U.S. Treasury yields with equivalent terms in effect at the time of the grant.

(3) Volatility is estimated based on volatility average of the Company’s common stock price.

(4) The computation of expected term was determined based on safe harbor rules, considering the contractual terms of the awards and vesting schedules.

(5) No options were granted during the year ended September 30, 2024 and September 30, 2022.

Summary of Share Activity Related to RSUs

The following table summarizes the activity of the Company’s RSUs:

			Number of RSUs						Weighted- Average Grant Date Fair Value
Outstanding as of September 30, 2023			4,241,640						$	58.43
Granted			1,939,025						30.53
Vested			(1,047,565)						51.90
Forfeited			(219,788)						40.43
Outstanding as of September 30, 2024			4,913,312						$	49.61

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