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Insider Trading Arrangements
 3 Months Ended 6 Months Ended
Mar. 31, 2024
shares
Mar. 31, 2024
shares
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
During the quarter ended March 31, 2024, the following directors and officers (as defined in Exchange Act Rule 16a-1(f)) adopted certain trading plans intended to satisfy Rule 10b5-1(c):
NameTitleAdoption DatePlan Start DatePlan End Date
Shares
Vesting and
Subject to
Sell-To-
Cover (1)
Other
Shares
Being Sold
(Subject to
Certain
Conditions)
James HamiltonChief Discovery and Translational Medicine3/26/20241/6/20251/17/202560,000n/a
Ken MyszkowskiChief Financial Officer3/12/20246/11/20242/28/2025n/a115,000
Ken MyszkowskiChief Financial Officer3/28/20241/6/20251/17/202515,000n/a
Ken MyszkowskiChief Financial Officer3/28/20241/6/20251/17/202515,000n/a
Ken MyszkowskiChief Financial Officer3/28/20241/6/20251/17/202515,000n/a
Ken MyszkowskiChief Financial Officer3/28/20241/6/20251/17/202518,750n/a
Patrick O'BrienChief Operating Officer and General Counsel3/21/20241/6/20251/17/202567,500n/a
William WaddillBoard Member3/27/202412/16/202412/31/2024n/a7,495
(1) This column indicates the total number of shares vesting in connection with equity awards, not the number of shares to be sold. The actual number of shares to be sold will be a smaller number based on whatever is required to satisfy payment of applicable withholding taxes under sell-to-cover arrangements.
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
James Hamilton [Member]    
Trading Arrangements, by Individual    
Name James Hamilton  
Title Chief Discovery and Translational Medicine  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/26/2024  
Arrangement Duration 11 days  
Aggregate Available 60,000 60,000
Patrick O'Brien [Member]    
Trading Arrangements, by Individual    
Name Patrick O'Brien  
Title Chief Operating Officer and General Counsel  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/21/2024  
Arrangement Duration 11 days  
Aggregate Available 67,500 67,500
William Waddill [Member]    
Trading Arrangements, by Individual    
Name William Waddill  
Title Board Member  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/27/2024  
Arrangement Duration 15 days  
Aggregate Available 7,495 7,495
Ken Myszkowski March 12 Plan [Member] | Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/12/2024  
Arrangement Duration 262 days  
Aggregate Available 115,000 115,000
Ken Myszkowski March 28 Plan 1 [Member] | Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/28/2024  
Arrangement Duration 11 days  
Aggregate Available 15,000 15,000
Ken Myszkowski March 28 Plan 2 [Member] | Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/28/2024  
Arrangement Duration 11 days  
Aggregate Available 15,000 15,000
Ken Myszkowski March 28 Plan 3 [Member] | Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/28/2024  
Arrangement Duration 11 days  
Aggregate Available 15,000 15,000
Ken Myszkowski March 28 Plan 4 [Member] | Ken Myszkowski [Member]    
Trading Arrangements, by Individual    
Name Ken Myszkowski  
Title Chief Financial Officer  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 3/28/2024  
Arrangement Duration 11 days  
Aggregate Available 18,750 18,750