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v3.25.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES: |  |
Net loss | $ (175,218) | $ (135,376)
Adjustments to reconcile net loss to net cash flow from operating activities |  |
Stock-based compensation | 15,209 | 19,694
Depreciation and amortization | 5,235 | 4,263
Accretion of note premiums/discounts | (5,704) | (835)
Realized loss on investments | 0 | (80)
Non-cash interest expense on liability related to the sale of future royalties | 5,415 | 5,367
Non-cash interest expense on credit facility | 16,231 | 0
Changes in operating assets and liabilities: |  |
Accounts receivable | (2,500) | 0
Prepaid expenses and other assets | (592) | (1,748)
Accounts payable | 3,069 | (12,463)
Accrued expenses | (7,691) | 408
Deferred revenue | 0 | (866)
Operating lease, net | (1,128) | 3,796
Other | 1,402 | 0
Net cash used in operating activities | (146,272) | (117,840)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |
Purchases of property and equipment | (7,516) | (68,656)
Purchases of investments | (33,749) | 0
Proceeds from sales and maturities of investments | 118,175 | 133,495
Net cash provided by investing activities | 76,910 | 64,839
CASH FLOWS FROM FINANCING ACTIVITIES: |  |
Proceeds from the exercises of stock options | 634 | 267
Proceeds from the issuance of pre-funded warrants | 25,000 | 0
Payments of debt issuance cost | (5,000) | 0
Net cash provided by financing activities | 20,634 | 267
Net decrease in cash, cash equivalents and restricted cash | (48,728) | (52,734)
Effect of exchange rate on cash, cash equivalents and restricted cash | (68) | 58
CASH, CASH EQUIVALENTS AND RESTRICTED CASH: |  |
BEGINNING OF PERIOD | 102,685 | 110,891
END OF PERIOD | 53,889 | 58,215
Supplementary disclosure of cash flows: |  |
Income taxes paid | (11) | (999)
Supplemental disclosure of non-cash investing activities: |  |
Capital expenditures included in accrued expenses | $ 2,574 | $ 11,290

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