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Collaboration and License Agreements - Takeda Pharmaceutical Company Limited (Details) | 1 Months Ended |  |  |
--- | --- | --- | --- | ---
Oct. 31, 2020 USD ($) bundle | Dec. 31, 2024 USD ($) | Sep. 30, 2024 USD ($) | Mar. 31, 2023 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Development regulatory and sales milestones payments |  | $ 14,100,000,000 |  |
Accrued expenses |  | 59,401,000 | $ 63,017,000 |
Takeda | License and Co-Funding Agreement |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Number of distinct bundle | bundle | 1 |  |  |
Initial transaction price | $ 300,000,000 |  |  |
Milestone payment |  |  |  | $ 40,000,000
Contract liabilities |  | 0 |  |
Accrued expenses |  | 33,600,000 |  |
Takeda | License and Co-Funding Agreement | Minimum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 20.00% |  |  |
Takeda | License and Co-Funding Agreement | Maximum |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |
Percentage of eligible to receive tiered royalties on net sales | 25.00% |  |  |
Development regulatory and sales milestones payments |  | $ 527,500,000 |  |

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