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Selected Quarterly Financial Information (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Selected Quarterly Financial Information (Unaudited)                      
Net sales $ 73,240 $ 74,710 $ 78,093 $ 67,968 $ 73,234 $ 64,831 $ 31,558 $ 55,336 $ 294,011 $ 224,959 $ 236,984
Cost of sales 16,865 15,370 17,759 16,633 19,590 17,932 21,668 32,529 66,627 91,719 38,588
Gross profit 56,375 59,340 60,334 51,335 53,644 46,899 9,890 22,807 227,384 133,240 198,396
Operating expenses:                      
Selling, general and administrative 47,566 44,470 45,300 41,921 43,792 38,947 38,116 50,546 179,257 171,401 176,635
Research and development 26,678 28,846 24,256 21,219 21,244 20,304 18,971 24,873 100,999 85,392 68,308
In-process research and development   5,000 5,000           10,000   3,745
Litigation-related settlement   (30,000)             (30,000)    
Total operating expenses 74,244 48,316 74,556 63,140 65,036 59,251 57,087 75,419 260,256 256,793 248,688
Loss from operations (17,869) 11,024 (14,222) (11,805) (11,392) (12,352) (47,197) (52,612) (32,872) (123,553) (50,292)
Non-operating income (expense) (4,366) (4,592) (3,052) (4,385) (2,499) (4,285) (81) (1,896) (16,395) (8,761) 256
Provision for income taxes (363) 202 208 279 (3,243) (889) (7,384) (450) 326 (11,966) (65,460)
Net (loss) income $ (21,872) $ 6,230 $ (17,482) $ (16,469) $ (10,648) $ (15,748) $ (39,894) $ (54,058) $ (49,593) $ (120,348) $ 15,424
Basic net (loss) income per share (in dollars per share) $ (0.47) $ 0.13 $ (0.38) $ (0.36) $ (0.24) $ (0.35) $ (0.90) $ (1.24) $ (1.07) $ (2.70) $ 0.41
Diluted net (loss) income per share (in dollars per share) $ (0.47) $ 0.13 $ (0.38) $ (0.36) $ (0.24) $ (0.35) $ (0.90) $ (1.24) $ (1.07) $ (2.70) $ 0.37