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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating Activities      
Net (loss) income $ (49,593) $ (120,348) $ 15,424
Adjustments to reconcile net (loss) income to net cash provided by (used in) operating activities:      
Depreciation and amortization 29,661 29,381 6,306
Amortization of the fair market value inventory adjustment as a result of the Avedro Merger   24,712 4,026
Amortization of right-of-use lease assets 4,760 5,232 3,557
Amortization of debt issuance costs 1,373 364  
Amortization of debt discount   5,610  
Deferred income tax benefit (1,029) (12,176) (66,306)
Loss on disposal of fixed assets 7 367 430
Stock-based compensation 30,146 46,477 36,393
Change in fair value of cash settled stock options   (3,172) 3,088
Unrealized foreign currency losses (gains) 2,313 (1,202) 194
Amortization of premium (discount) on short-term investments 1,028 453 (338)
Other liabilities 2,465 4,538 5,352
Changes in operating assets and liabilities:      
Accounts receivable, net 1,700 2,243 (6,632)
Inventory (7,703) 1,962 52
Prepaid expenses and other current assets (3,054) (5,033) (917)
Accounts payable and accrued liabilities 12,448 (2,683) 779
Other assets 186 287 (1,777)
Net cash provided by (used in) operating activities 24,708 (22,988) (369)
Investing activities      
Cash acquired due to acquisition     49,652
Purchases of property and equipment (47,785) (6,935) (4,724)
Purchases of short-term investments (215,285) (301,002) (80,388)
Proceeds from sales and maturities of short-term investments 206,916 104,697 80,494
Proceeds from disposal of property and equipment 3    
Investment in company-owned life insurance (2,081) (1,820) (1,608)
Net cash (used in) provided by investing activities (58,232) (205,060) 43,426
Financing activities      
Proceeds from convertible senior notes   287,500  
Payment of convertible senior notes transaction costs   (9,614)  
Purchase of capped calls related to issuance of convertible senior notes   (35,679)  
Proceeds from exercise of stock options 26,124 20,196 15,064
Share purchases under Employee Stock Purchase Plan 4,817 4,025 3,388
Payment of employee taxes related to vested restricted stock units (3,690) (3,886) (5,601)
Payment of debt assumed in the Avedro Merger     (22,496)
Proceeds from tenant improvement allowance 12,668    
Principal paid on finance lease (659)    
Net cash provided by (used in) financing activities 39,260 262,542 (9,645)
Effect of exchange rate changes on cash and cash equivalents (1,774) (88) (252)
Net increase in cash, cash equivalents and restricted cash 3,962 34,406 33,160
Cash, cash equivalents and restricted cash at beginning of period 106,162 71,756 38,596
Cash, cash equivalents and restricted cash at end of period 110,124 106,162 71,756
Supplemental schedule of noncash investing and financing activities      
Shares issued and Replacement Awards assumed in connection with Avedro Merger     437,751
Debt assumed in the Avedro Merger     22,496
Purchase of property and equipment included in accounts payable and accrued liabilities 2,263 641 995
Supplemental disclosures of cash flow information      
Taxes paid, net of refunds 272 484 171
Interest paid on convertible senior notes 7,907 4,041 $ 2
Other interest paid $ 4,074 $ 1,334