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Leases - Additional Information (Details)
$ in Thousands
 1 Months Ended 12 Months Ended
Feb. 28, 2022
Jan. 31, 2021
RenewalOption
Nov. 30, 2020
Jul. 31, 2019
Jul. 31, 2016
RenewalOption
Dec. 31, 2021
USD ($)
Lease
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jan. 01, 2021
USD ($)
Lessee Lease Description [Line Items]                  
Operating lease, ROU assets           $ 27,958     $ 900
Operating lease liabilities           $ 16,783     900
Number of operating lease | Lease           2      
Operating leases, rent expense recognized           $ 3,200 $ 700 $ 600  
ASU 2016-02                  
Lessee Lease Description [Line Items]                  
Operating lease, ROU assets                 900
Operating lease liabilities                 $ 900
Headquarters Facility                  
Lessee Lease Description [Line Items]                  
Operating lease, agreement term         5 years        
Operating lease, commencement date         Sep. 01, 2016        
Lease expiration date         Aug. 31, 2021        
Operating lease, renewal option | RenewalOption         2        
Operating lease, renewal term         30 months        
Operating lease, option to renewal, description           30-month renewal options      
Operating lease, existence of option to renewal         true        
Operating lease, description           In July 2016, we entered into a five-year lease agreement for our previous headquarters facility located in Foster City, California. The original term of the lease was from September 1, 2016 to August 31, 2021, with two 30-month renewal options.      
Operating lease, extended term     6 months            
Operating lease, extended maturity date     Mar. 01, 2022            
Headquarters Facility | Subsequent Event                  
Lessee Lease Description [Line Items]                  
Lease termination date Feb. 12, 2022                
Additional Facility                  
Lessee Lease Description [Line Items]                  
Operating lease, commencement date       Jul. 01, 2019          
Lease expiration date       Oct. 31, 2021          
Operating lease, option to renewal, description           no renewal options      
Operating lease, existence of option to renewal       false          
Operating lease, description           In July 2019, we leased another facility in Foster City, California as a result of growth in personnel and lab space requirements. The original term of this lease was from July 1, 2019 to October 31, 2021, with no renewal options.      
Operating lease, extended term     6 months            
Operating lease, extended maturity date     Apr. 30, 2022            
Office                  
Lessee Lease Description [Line Items]                  
Lease expiration date           Apr. 30, 2021      
New Corporate Headquarters Facility                  
Lessee Lease Description [Line Items]                  
Operating lease, commencement date   Jan. 22, 2021              
Lease expiration date   Dec. 31, 2025              
Operating lease, renewal term   60 months              
Operating lease, extended term   60 days              
Number of renewal options | RenewalOption   2              
Palo Alto                  
Lessee Lease Description [Line Items]                  
Operating lease, extended maturity date   Mar. 03, 2022              
Operating lease, ROU assets           $ 300      
Operating lease liabilities           300      
San Carlos                  
Lessee Lease Description [Line Items]                  
Operating lease, ROU assets           28,400      
Operating lease liabilities           $ 12,900