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Income Taxes - Reconciliation of Effective Tax Rate (Details)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	[1]	Dec. 31, 2019	[1]
Effective Income Tax Rate Continuing Operations Tax Rate Reconciliation [Abstract]
Statutory Rate	21.00%	21.00%		21.00%
Stock-based Compensation	2.20%	0.80%		(0.40%)
Credits	1.10%	0.60%		(0.50%)
Change in Fair Value of Tranche Liability	0.00%	0.00%		1.30%
Change in valuation allowance	(23.00%)	(22.10%)		(21.80%)
Section 162(m) Limitation	(1.10%)	(0.10%)		0.00%
Other	(0.20%)	(0.20%)		0.40%
Total	0.00%	0.00%		0.00%
[1] The 2019 and 2020 effective tax rate reconciliations have been updated to conform to the 2021 presentation.

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Effective income tax rate reconciliation change in fair value of tranche liability.

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Section 162(m) limitation.

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- Definition

Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying domestic federal statutory income tax rate to pretax income (loss) from continuing operation, attributable to nondeductible expense for share-based payment arrangement.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to tax credits. Including, but not limited to, research credit, foreign tax credit, investment tax credit, and other tax credits.

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