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Balance Sheet Details | 12 Months Ended
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Dec. 31, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
Balance Sheet Details | 4. Balance Sheet Details Property and Equipment, Net Property and equipment, net as of December 31, 2022 and 2021 consisted of the following:
|  | December 31, |
|  | 2022 |  |  | 2021 |
|  | (in thousands) |
Furniture and equipment |  | $ | 1,608 |  |  | $ | 1,619 |
Computers and computer software |  |  | 416 |  |  |  | 430 |
Lab equipment |  |  | 13,100 |  |  |  | 9,453 |
Leasehold improvements |  |  | 1,353 |  |  |  | — |
Total property and equipment |  |  | 16,477 |  |  |  | 11,502 |
Less: accumulated depreciation and amortization |  |  | (6,117 | ) |  |  | (3,548 | )
Property and equipment, net |  | $ | 10,360 |  |  | $ | 7,954 |
Depreciation and amortization expense for the years ended December 31, 2022, 2021 and 2020 was $2.6 million, $1.8 million and $1.4 million respectively. Accrued Expenses Accrued expenses as of December 31, 2022 and 2021 consisted of the following:
|  | December 31, |
|  | 2022 |  |  | 2021(2) |
|  | (in thousands) |
Clinical studies |  | $ | 1,518 |  |  | $ | 453 |
Other research and development (1) |  |  | 12,446 |  |  |  | 4,676 |
Other accrued expenses |  |  | 1,411 |  |  |  | 3,658 |
Total |  | $ | 15,375 |  |  | $ | 8,787 |
______________ (1) Includes $5.0 million and $0 of accrued manufacturing rights as of December 31, 2022 and 2021, respectively. See Note 6, "Commitments and Contingencies, Sutro Option Agreement," for further details. (2) The breakout and categorizations of the 2021 total accrued expenses have been updated to conform to the 2022 presentation.

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- Definition The entire disclosure for supplemental balance sheet disclosures, including descriptions and amounts for assets, liabilities, and equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -URI https://asc.fasb.org/topic&trid=2122208 + Details
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