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Net Loss Per Share | 12 Months Ended
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Dec. 31, 2022
Earnings Per Share [Abstract] |
Net Loss Per Share | 13. Net Loss Per Share The following table sets forth the computation of basic and diluted net loss per share and excludes shares which are legally outstanding, but subject to repurchase by us:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |  |  | 2020 |
Net loss (in thousands) |  | $ | (223,485 | ) |  | $ | (100,077 | ) |  | $ | (89,217 | )
Weighted-average shares outstanding used in computing net loss per share, basic and diluted(1) |  |  | 64,877,988 |  |  |  | 51,922,108 |  |  |  | 29,545,810 |
Net loss per share, basic and diluted |  | $ | (3.44 | ) |  | $ | (1.93 | ) |  | $ | (3.02 | )
____________________________ (1) Includes shares of common stock into which pre-funded warrants may be exercised. See Note 9, "Pre-Funded Warrants". The following potentially dilutive securities were excluded from the computation of diluted net loss per share for the period presented because including them would have been antidilutive:
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |  |  | 2020 |
Stock options |  |  | 7,752,204 |  |  |  | 5,357,389 |  |  |  | 5,188,531 |
Restricted stock units |  |  | 456,766 |  |  |  | — |  |  |  | - |
Employee stock purchase plans |  |  | 113,240 |  |  |  | 66,404 |  |  |  | 87,887 |
Total |  |  | 8,322,210 |  |  |  | 5,423,793 |  |  |  | 5,276,418 |

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