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Balance Sheet Details

12 Months Ended

Dec. 31, 2022

Organization, Consolidation and Presentation of Financial Statements [Abstract]

4. Balance Sheet Details

Property and Equipment, Net

Property and equipment, net as of December 31, 2022 and 2021 consisted of the following:


	December 31,
	2022			2021
	(in thousands)
Furniture and equipment	$	1,608		$	1,619
Computers and computer software		416			430
Lab equipment		13,100			9,453
Leasehold improvements		1,353			—
Total property and equipment		16,477			11,502
Less: accumulated depreciation and amortization		(6,117	)		(3,548	)
Property and equipment, net	$	10,360		$	7,954

Depreciation and amortization expense for the years ended December 31, 2022, 2021 and 2020 was $2.6 million, $1.8 million and $1.4 million respectively.

Accrued Expenses

Accrued expenses as of December 31, 2022 and 2021 consisted of the following:


	December 31,
	2022		2021(2)
	(in thousands)
Clinical studies	$	1,518	$	453
Other research and development (1)		12,446		4,676
Other accrued expenses		1,411		3,658
Total	$	15,375	$	8,787

______________

(1)

Includes $5.0 million and $0 of accrued manufacturing rights as of December 31, 2022 and 2021, respectively. See Note 6, "Commitments and Contingencies, Sutro Option Agreement," for further details.

(2)

The breakout and categorizations of the 2021 total accrued expenses have been updated to conform to the 2022 presentation.