    <SEC-DOCUMENT>0000950170-23-015477-index.html : 20230428
    <SEC-HEADER>0000950170-23-015477.hdr.sgml : 20230428
    <ACCEPTANCE-DATETIME>20230428071553
    ACCESSION NUMBER:		0000950170-23-015477
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20221231
    FILED AS OF DATE:		20230428
    DATE AS OF CHANGE:		20230428
    EFFECTIVENESS DATE:		20230428

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Vaxcyte, Inc.
    		CENTRAL INDEX KEY:			0001649094
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				464233385
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39323
    		FILM NUMBER:		23860133

    	BUSINESS ADDRESS:
    		STREET 1:		825 INDUSTRIAL ROAD, STE. 300
    		CITY:			SAN CARLOS
    		STATE:			CA
    		ZIP:			94070
    		BUSINESS PHONE:		650-837-0111

    	MAIL ADDRESS:
    		STREET 1:		825 INDUSTRIAL ROAD, STE. 300
    		CITY:			SAN CARLOS
    		STATE:			CA
    		ZIP:			94070

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	SutroVax, Inc.
    		DATE OF NAME CHANGE:	20150724
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>2022_10k_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: 2022_10k_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>