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Share-Based Compensation - Additional Information (Details) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2021 shares | Mar. 31, 2022 USD ($) condition shares | Mar. 31, 2021 USD ($) | Dec. 31, 2021 USD ($) condition $ / shares shares | Dec. 31, 2020 USD ($) $ / shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 4,481 |  | $ 757 | $ 6,754 | $ 1,051
2022 Equity Incentive Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Vesting period |  | 3 years |  |  |  |
Restricted stock units, granted | shares |  | 4,296,875 |  |  |  |
2017 Equity Incentive Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Restricted stock units, outstanding | shares |  | 6,269,300 |  |  |  |
Number of shares issued under share-based payment arrangement. | shares |  |  |  |  | 7,927,329 |
unrecognized compensation cost related to unvested share-based compensation arrangements |  |  |  |  | $ 19,600 |
Board of Directors |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Anniversary period |  | 10 years |  |  |  |
Board of Directors | 2022 Equity Incentive Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Restricted stock units, granted | shares |  | 4,296,875 |  |  |  |
Percentage increase in common stock reserve for future issuance |  | 5.00% |  |  |  |
Research and Development |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 1,300 |  | 200 | 1,930 | 500
General and Administrative |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | 3,200 |  | 600 | 4,824 | 551
Stock Options |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 3,030 |  | $ 757 | $ 6,800 | $ 1,100
weighted average grant date fair value per share | $ / shares |  |  |  |  | $ 5.77 | $ 3.19
Aggregate grant date fair value of stock options vested |  |  |  |  | $ 5,300 | $ 1,700
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition |  |  |  |  | 2 years 9 months 18 days |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value |  |  |  |  | $ 1,000 | $ 500
Stock Options | 2017 and 2022 Equity Incentive Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Expiration period |  | 10 years |  |  | 10 years |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value |  | $ 16,304 | [1] |  | $ 5,011 |
Stock Options | 2017 and 2022 Equity Incentive Plan | Minimum |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Vesting period |  | 3 years |  |  | 3 years |
Stock Options | 2017 and 2022 Equity Incentive Plan | Maximum |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Vesting period |  | 4 years |  |  | 4 years |
Restricted Stock Units |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 696 |  |  | $ 0 |
Restricted Stock Units | 2022 Equity Incentive Plan |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Restricted stock units, granted | shares |  | 703,329 |  |  |  |
Restricted stock units, outstanding | shares |  | 702,663 |  |  |  |
Restricted Stock Units | Executive Officer |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 755 |  |  |  |
Restricted stock units, granted | shares | 952,804 |  |  |  |  |
Vesting description |  | Each RSU granted in the RSU Award entitles the recipient to one share of common stock upon vesting subject to the service, performance, and market conditions. |  |  |  |
Restricted stock units, outstanding | shares |  | 952,804 |  |  | 952,804 |
Restricted stock units, vested | shares |  | 0 |  |  | 0 |
Restricted stock units, exercisable | shares |  | 0 |  |  | 0 |
Number of performance condition scenarios | condition |  | 3 |  |  | 3 |
Restricted Stock Units | IPO |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Expiration period |  |  |  |  | 10 years |
Restricted Stock Units | IPO | Executive Officer |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Vesting description |  | Upon an IPO, (i) one-sixth of the RSU Award will vest if a minimum Enterprise Value of $2.5 billion is achieved, (ii) all the RSU Award will vest if a $5.0 billion Enterprise Value is achieved, and (iii) a portion of the RSU Award will vest based on a straight-line interpolation if an Enterprise Value of between $2.5 billion and $5.0 billion is achieved. |  |  | Upon an IPO, (i) one-sixth of the RSU Award will vest if a minimum Enterprise Value of $2.5 billion is achieved, (ii) all the RSU Award will vest if a $5.0 billion Enterprise Value is achieved, and (iii) a portion of the RSU Award will vest based on a straight-line interpolation if an Enterprise Value of between $2.5 billion and $5.0 billion is achieved. |
Anticipated service period |  | 10 years |  |  |  |
Fair value of the RSU award |  | $ 10,300 |  |  |  |
Restricted Stock Units | Change in Control | Executive Officer |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Vesting description |  | Upon a Change in Control, (i) one-sixth of the RSU Award will vest if a minimum Change in Control Market Capitalization of $2.5 billion is achieved, (ii) all of the RSU Award will vest if a $5.0 billion Change in Control Market Capitalization is achieved, and (iii) a portion of the RSU Award will vest based on a straight-line interpolation if a Change in Control Market Capitalization of between $2.5 billion and $5.0 billion is achieved based on a straight-line interpolation. |  |  | Upon a Change in Control, (i) one-sixth of the RSU Award will vest if a minimum Change in Control Market Capitalization of $2.5 billion is achieved, (ii) all of the RSU Award will vest if a $5.0 billion Change in Control Market Capitalization is achieved, and (iii) a portion of the RSU Award will vest based on a straight-line interpolation if a Change in Control Market Capitalization of between $2.5 billion and $5.0 billion is achieved based on a straight-line interpolation. |
Restricted Stock Units | General and Administrative | Executive Officer |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |  |  |
Share-based compensation expense |  | $ 800 |  |  |  |
[1] | The aggregate intrinsic value is calculated as the difference between the exercise price of the underlying options and the estimated fair value of the common stock for the options that were in the money as of March 31, 2022.

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