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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (unaudited) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Revenues [Abstract]        
Revenue $ 0 $ 0 $ 0 $ 0
Operating expenses:        
Research and development 24,401 8,521 46,883 25,056
General and administrative 8,034 2,761 18,135 7,040
Total operating expenses 32,435 11,282 65,018 32,096
Loss from operations (32,435) (11,282) (65,018) (32,096)
Other income, net 50 1 49 1
Net loss (32,385) (11,281) (64,969) (32,095)
Other comprehensive loss:        
Unrealized loss on marketable securities 24 0 20 0
Comprehensive loss $ (32,409) $ (11,281) $ (64,989) $ (32,095)
Net loss per share attributable to common stockholders—basic and diluted $ (1.56) $ (33.45) $ (145.55) $ (112.18)
Weighted-average common shares outstanding—basic and diluted 20,760,722 337,302 446,379 286,105