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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities        
Net loss $ (32,385) $ (11,281) $ (64,969) $ (32,095)
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation and amortization 416 207 1,041 629
Noncash operating lease expense 60      
Amortization of premiums and discounts on marketable securities 110   210  
Share-based compensation 4,481 757 6,754 1,051
Loss on disposal of property and equipment     3  
Changes in operating assets and liabilities:        
Prepaid expenses and other current and non-current assets (8,423) 48 (6,059) 331
Accounts payable and other current liabilities 696 321 974 (1,333)
Accrued liabilities 2,563 392 7,764 2,776
Operating lease liabilities (104)      
Deferred rent   49 44 (21)
Net cash used in operating activities (32,586) (9,507) (54,238) (28,662)
Cash flows from investing activities        
Purchases of property and equipment (467) (1,066) (5,783) (888)
Purchases of marketable securities (27,026)   (74,193)  
Proceeds from maturities of marketable securities 16,850      
Net cash used in investing activities (10,643) (1,066) (79,976) (888)
Cash flows from financing activities        
Payments under capital leases     (387)  
Proceeds from the exercise of stock options 429 7 432 40
Payments of deferred offering costs   (14) (688) (1,185)
Payment for repurchase of restricted stock     (24)  
Proceeds from issuance of Series C redeemable convertible preferred stock, net of transaction costs   81,756    
Proceeds from issuance of common stock (initial public offering), net of transactions costs 129,156      
Proceeds from issuance of common stock (private placement), net of transactions costs 10,000      
Payments under finance leases (29) (121)    
Net cash provided by financing activities 139,556 81,628 118,451 41,656
Net increase in cash and cash equivalents and restricted cash 96,327 71,055 (15,763) 12,106
Cash and cash equivalents and restricted cash, beginning of the year 31,032 46,795 46,795 34,689
Cash and cash equivalents and restricted cash, end of the period 127,359 117,850 31,032 46,795
Supplemental disclosures of noncash investing and financing activities:        
Purchase of property and equipment included in accounts payable and accrued liabilities 35 $ 238 278 311
Deferred offering costs included in accrued liabilities $ 42   1,301 576
Series B Redeemable Convertible Preferred Stock        
Cash flows from financing activities        
Proceeds from issuance of Series C redeemable convertible preferred stock, net of transaction costs       $ 42,801
Series C Redeemable Convertible Preferred Stock        
Cash flows from financing activities        
Proceeds from issuance of Series C redeemable convertible preferred stock, net of transaction costs     $ 119,118