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Nature of the Business - Additional Information (Details) - USD ($) $ in Thousands |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | ---
Jan. 26, 2023 | Jan. 31, 2023 | Mar. 31, 2022 | Mar. 31, 2023 | Dec. 31, 2022
Class of Stock [Line Items] |  |  |  |  |
Accumulated Deficit |  |  |  | $ (346,134) | $ (318,790)
Proceeds from issuance of private placement and non-refundable upfront payment |  | $ 325,000 |  |  |
Proceeds from issuance of private placement |  |  | $ 10,000 |  |
Cash, cash equivalents and marketable securities |  |  |  | $ 533,600 |
Kite Collaboration Agreement |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |
Non-refundable upfront payment received |  | 225,000 |  |  |
Private Placement | Gilead Common Stock Purchase Agreement |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |
Proceeds from issuance of private placement | $ 100,000 | $ 100,000 |  |  |

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