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Nature of the Business - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Jan. 26, 2023
Jan. 31, 2023
Mar. 31, 2022
Mar. 31, 2023
Dec. 31, 2022
Class of Stock [Line Items]          
Accumulated Deficit       $ (346,134) $ (318,790)
Proceeds from issuance of private placement and non-refundable upfront payment   $ 325,000      
Proceeds from issuance of private placement     $ 10,000    
Cash, cash equivalents and marketable securities       $ 533,600  
Kite Collaboration Agreement          
Class of Stock [Line Items]          
Non-refundable upfront payment received   225,000      
Private Placement | Gilead Common Stock Purchase Agreement          
Class of Stock [Line Items]          
Proceeds from issuance of private placement $ 100,000 $ 100,000