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Segment Reporting | 12 Months Ended
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Dec. 31, 2024
Segment Reporting [Abstract] |
Segment Reporting | 17. Segment Reporting The Company operates in a single operating segment and has one reportable segment, which includes all activities related to the discovery, development, and manufacturing of its product candidates. The determination of a single segment is consistent with the consolidated financial information regularly provided to the Company's chief operating decision maker ("CODM"). The Company’s CODM is its chief executive officer. The CODM uses consolidated net loss for purpose of assessing performance, making operating decisions and allocating resources. The measurement of segment assets is reported on the balance sheet as total consolidated assets. The table below provides information about the Company’s segment (in thousands):
| Year Ended December 31, |
| 2024 |  |  | 2023 |  |  | 2022 |
Collaboration revenue | $ | 107,936 |  |  | $ | 110,319 |  |  | $ | — |
Operating expenses: |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |
anito-cel in rrMM |  | 50,141 |  |  |  | 73,530 |  |  |  | 96,513 |
ACLX-001 |  | 1,975 |  |  |  | 2,939 |  |  |  | 8,764 |
ACLX-002 |  | 14,294 |  |  |  | 5,667 |  |  |  | 6,458 |
Other research and development costs |  | 21,364 |  |  |  | 3,701 |  |  |  | 5,467 |
Internal costs [1] |  | 69,319 |  |  |  | 48,012 |  |  |  | 32,353 |
General and administrative |  | 88,414 |  |  |  | 66,350 |  |  |  | 41,704 |
Total operating expenses |  | 245,507 |  |  |  | 200,199 |  |  |  | 191,259 |
Loss from operations |  | (137,571 | ) |  |  | (89,880 | ) |  |  | (191,259 | )
Interest and other income (expense), net |  | 33,322 |  |  |  | 23,695 |  |  |  | 4,300 |
Interest expense |  | (1,030 | ) |  |  | (3,842 | ) |  |  | (1,720 | )
Total other income, net |  | 32,292 |  |  |  | 19,853 |  |  |  | 2,580 |
Income tax expense |  | (2,069 | ) |  |  | (663 | ) |  |  | — |
Net loss | $ | (107,348 | ) |  | $ | (70,690 | ) |  | $ | (188,679 | )
[1]Internal costs primarily consist of employee-related costs, including salaries, related benefits, and share-based compensation expense, as well as facility allocation and depreciation expense.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 55 -Paragraph 48 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482785/280-10-55-48 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards 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