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Related Parties - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2023 | Jan. 31, 2023 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Related Party Transaction [Line Items] |  |  |  |  |
Proceeds from issuance of private placement |  |  |  | $ 299,706 | $ 9,958
Contract liability | $ 221,206 |  | $ 135,051 | 221,206 |
Contract liability, long-term portion | $ 170,673 |  | 75,995 | 170,673 |
Collaboration revenue from related party |  |  | $ 107,936 | $ 110,319 |
Gilead |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Percentage of ownership held |  |  | 13.00% |  |
Contract liability |  |  | $ 135,100 |  |
Contract liability, long-term portion |  |  | $ 76,000 |  |
Gilead Common Stock Purchase Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Shares purchased |  |  | 3,478,261 |  |
Shares issued, price per share |  |  | $ 28.75 |  |
Gilead Common Stock Purchase Agreement | Gilead |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Proceeds from issuance of private placement |  | $ 100,000 |  |  |
Second Gilead Common Stock Purchase Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Shares purchased | 3,242,542 |  | 3,242,542 | 3,242,542 |
Shares issued, price per share | $ 61.68 |  | $ 61.68 | $ 61.68 |
Second Gilead Common Stock Purchase Agreement | Gilead |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Proceeds from issuance of private placement | $ 200,000 |  |  |  |
Gilead Collaboration Agreement |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |
Collaboration revenue from related party |  |  | $ 107,900 |  |

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