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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Statement [Abstract]      
Collaboration revenue from related party $ 107,936 $ 110,319  
Operating expenses:      
Research and development 157,093 133,849 $ 149,555
General and administrative 88,414 66,350 41,704
Total operating expenses 245,507 200,199 191,259
Loss from operations (137,571) (89,880) (191,259)
Other income (expense):      
Interest and other income (expense) 33,322 23,695 4,300
Interest expense (1,030) (3,842) (1,720)
Total other income, net 32,292 19,853 2,580
Loss before income taxes (105,279) (70,027) (188,679)
Income tax expense (2,069) (663)  
Net loss (107,348) (70,690) (188,679)
Other comprehensive loss:      
Unrealized gain (loss) on marketable securities 301 768 (201)
Comprehensive loss $ (107,047) $ (69,922) $ (188,880)
Net loss per share attributable to common stockholders - basic $ (2) $ (1.47) $ (5.19)
Net loss per share attributable to common stockholders - diluted $ (2) $ (1.47) $ (5.19)
Weighted-average common shares outstanding - basic 53,566,153 48,061,450 36,355,758
Weighted-average common shares outstanding - diluted 53,566,153 48,061,450 36,355,758