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Share-Based Compensation - Schedule of Share-based Compensation Expense reflected in the consolidated statement of operations and comprehensive loss (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Share-Based Payment Arrangement, Expense $ 61,086 $ 41,789 $ 21,544
Research and Development Expense      
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Share-Based Payment Arrangement, Expense 21,359 11,003 7,007
General and Administrative Expense      
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]      
Share-Based Payment Arrangement, Expense $ 39,727 $ 30,786 $ 14,537