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Segment Reporting - Schedule of Segment Reporting (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
Collaboration revenue $ 107,936 $ 110,319  
Operating expenses:      
Research and development 157,093 133,849 $ 149,555
General and administrative 88,414 66,350 41,704
Total operating expenses 245,507 200,199 191,259
Loss from operations (137,571) (89,880) (191,259)
Interest and other income (expense), net 33,322 23,695 4,300
Interest expense (1,030) (3,842) (1,720)
Total other income, net 32,292 19,853 2,580
Income tax expense (2,069) (663)  
Net loss (107,348) (70,690) (188,679)
Anito-cel in rrMM      
Operating expenses:      
Research and development 50,141 73,530 96,513
ACLX-001      
Operating expenses:      
Research and development 1,975 2,939 8,764
ACLX-002      
Operating expenses:      
Research and development 14,294 5,667 6,458
Other Research and Development Costs      
Operating expenses:      
Research and development 21,364 3,701 5,467
Internal Costs      
Operating expenses:      
Research and development $ 69,319 $ 48,012 $ 32,353