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v3.25.3

Segment Reporting - Schedule of Segment Reporting Presents Reportable Segment Profit and Loss (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Revenue |  | $ 2,764 | $ 3,741 | $ 36,341 | $ 39,678
Less: |  |  |  |  |
Research and development expenses |  | 74,094 | 60,410 | 232,737 | 168,431
Other external research and development expense | [1] | 21,950 | 22,699 | 71,634 | 58,377
Research and development compensation and related personnel expense | [2] | 22,323 | 18,549 | 66,330 | 56,266
Research and development overhead and administrative costs |  | 12,468 | 10,084 | 34,622 | 29,084
General and administrative | [3] | 17,336 | 15,455 | 51,252 | 47,202
Interest and other expense | [4] | 3,953 | 60 | 4,135 | 5,115
Plus: |  |  |  |  |
Interest income |  | 10,444 | 9,697 | 27,413 | 27,964
Segment net loss |  | (82,175) | (62,487) | (224,370) | (153,106)
STAT6 [Member] |  |  |  |  |
Less: |  |  |  |  |
Research and development expenses |  | $ 17,353 | $ 9,078 | $ 60,151 | $ 24,704
[1] | Certain prior period amounts have been recast to conform with current period presentation.
[2] | Research and development compensation and related personnel expense for the three months ended September 30, 2025 and 2024 is inclusive of $8.4 and $7.6 million of stock-based compensation expense, respectively. Research and development compensation and related personnel expense for the nine months ended September 30, 2025 and 2024 is inclusive of $23.9 and $20.9 million of stock-based compensation expense, respectively.
[3] | General and administrative expense for the three months ended September 30, 2025 and 2024 is inclusive of $7.4 million and $7.3 million of stock-based compensation expense, respectively. General and administrative expense for the nine months ended September 30, 2025 and 2024 is inclusive of $21.5 million and $20.3 million of stock-based compensation expense, respectively.
[4] | Other expense for the three and nine months ended September 30, 2025 is inclusive of a $3.9 million impairment of long-lived assets. Other expense for the nine months ended September 30, 2024 is inclusive of a $4.9 million impairment of long-lived assets

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