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Equity-Based Compensation - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 9 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024 | Mar. 31, 2025 | Aug. 20, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | $ 15,802 | $ 14,904 | $ 45,451 | $ 41,213 |  |
Research and Development Expense |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | 8,360 | 7,604 | 23,943 | 20,944 |  |
General and Administrative |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | 7,442 | 7,300 | 21,508 | 20,269 |  |
Employee Stock Option |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Intrinsic value of stock options exercised | $ 8,600 | $ 10,400 | $ 16,000 | $ 19,000 |  |
Weighted-average fair value of options granted | $ 33.67 | $ 29.36 | $ 22.73 | $ 26.03 |  |
Unrecognized stock-based compensation expense | $ 73,500 |  | $ 73,500 |  |  |
Unrecognized compensation cost, recognition period |  |  | 2 years 1 month 6 days |  |  |
Equity-based compensation expense | 12,545 | $ 12,382 | $ 36,506 | $ 34,985 |  |
Employee Stock Option | Research and Development Expense |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | 5,919 | 5,950 | 17,615 | 16,925 |  |
Employee Stock Option | General and Administrative |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | 6,626 | $ 6,432 | 18,891 | $ 18,060 |  |
Restricted Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Unrecognized stock-based compensation expense | $ 31,300 |  | $ 31,300 |  |  |
Unrecognized compensation cost, recognition period |  |  | 2 years 9 months 18 days |  |  |
Granted | 243,950 | 152,288 | 763,050 | 396,272 |  |
Equity-based compensation expense | $ 2,800 | $ 2,300 | $ 8,000 | $ 5,600 |  |
Restricted Stock | Research and Development Expense |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | 2,300 | 1,500 | 5,800 | 3,600 |  |
Restricted Stock | General and Administrative |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Equity-based compensation expense | $ 500 | $ 800 | $ 2,200 | $ 2,000 |  |
2020 Plan |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Number of shares authorized for issuance under plan |  |  |  |  |  | 4,457,370
Maximum number of shares to be issued, percentage |  |  | 4.00% |  |  |
Shares remaining available for future grants | 4,138,724 |  | 4,138,724 |  |  |
Performance stock options vesting |  |  |  |  | 40.00% |
Second clinical milestone vesting percentage |  |  |  |  | 40.00% |
Third clinical milestone vesting percentage |  |  |  |  | 20.00% |
Granted |  |  | 88,000 |  |  |
Option Indexed to Issuer's Equity, Strike Price |  |  | $ 30.17 |  |  |
Performance stock options outstanding | 88,000 |  | 88,000 |  |  |
2020 Plan | Restricted Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Granted | 0 | 0 | 285,723 | 0 |  |
2020 Plan | Performance Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Performance stock options vesting |  |  |  |  | 40.00% |
Second clinical milestone vesting percentage |  |  |  |  | 40.00% |
Third clinical milestone vesting percentage |  |  |  |  | 20.00% |
Option Indexed to Issuer's Equity, Strike Price |  |  | $ 30.17 |  |  |
2020 Plan | Minimum [Member] |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Performance stock options range |  |  |  |  | 0.00% |
2020 Plan | Minimum [Member] | Performance Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Performance stock options range |  |  |  |  | 0.00% |
2020 Plan | Maximum [Member] |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Performance stock options range |  |  |  |  | 100.00% |
2020 Plan | Maximum [Member] | Performance Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Performance stock options range |  |  |  |  | 100.00% |
2020 ESPP |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Number of shares authorized for issuance under plan |  |  |  |  |  | 445,653
Shares remaining available for future grants | 2,318,998 |  | 2,318,998 |  |  |
Share-based compensation, description |  |  | The 2020 ESPP initially reserved and authorized the issuance of up to a total of 445,653 shares of common stock to participating employees. The 2020 ESPP provides that the number of shares reserved and available for issuance will automatically increase on January 1, 2021 and each January 1 thereafter through January 1, 2030, by the lesser of (i) 438,898 shares of common stock, (ii) 1% of the Company’s outstanding number of shares of common stock on the immediately preceding December 31 or (iii) such lesser number of shares of common stock as determined by the administrator of the 2020 ESPP |  |  |
2020 ESPP | Lesser of Potential Outcome 1 |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Maximum number of shares to be issued, percentage |  |  | 1.00% |  |  |
Number of additional shares authorized |  |  | 438,898 |  |  |
2018 Plan | Restricted Stock |  |  |  |  |  |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] |  |  |  |  |  |
Granted |  |  | 1,048,773 |  |  |

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