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Collaborations - Additional Information (Details) - USD ($) $ in Thousands |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Jun. 25, 2025 | Jul. 07, 2020 | Jun. 30, 2025 | Mar. 31, 2026 | Mar. 31, 2025 | Sep. 30, 2023 | Dec. 31, 2025 | Dec. 31, 2023
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Revenue |  |  |  | $ 34,365 | $ 22,100 |  |  |
Milestone Two [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Revenue recognized recorded in deferred revenue |  |  |  | 0 | 19,800 |  |  |
Unconstrained Consideration |  |  |  |  |  |  |  | $ 55,000
Sanofi Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront payment |  | $ 150,000 |  |  |  |  |  |
Collaboration agreement transaction price |  | 150,000 |  |  |  |  |  |
Unconstrained Consideration |  |  |  |  | 20,000 |  |  |
Sanofi Agreement | Milestone One [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Collaboration revenue recognised |  |  |  |  |  | $ 40,000 |  |
Sanofi Agreement | Milestone Two [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Collaboration revenue recognised |  |  |  |  |  | $ 15,000 |  |
Sanofi Agreement | Collaboration Target 1 |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Collaboration agreement transaction price |  | 120,000 |  |  |  |  |  |
Revenue |  |  |  | 0 | $ 22,100 |  |  |
Deferred Revenue |  |  |  | 0 |  |  | $ 0 |
Sanofi Agreement | Collaboration Target 2 |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Collaboration agreement transaction price |  | 30,000 |  |  |  |  |  |
Sanofi Agreement | Maximum |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Development milestone payments |  | 1,480,000 | $ 975,000 |  |  |  |  |
Commercial Milestone Payments |  | $ 700,000 |  |  |  |  |  |
Gilead Agreement |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront payment | $ 40,000 |  |  |  |  |  |  |
Collaboration agreement transaction price |  |  |  | 40,000 |  |  |  |
Revenue recognized recorded in deferred revenue |  |  |  | 0 |  |  | $ 34,400 |
Option Exercise Payment | 45,000 |  |  |  |  |  |  |
Revenue |  |  |  | $ 34,400 |  |  |  |
Gilead Agreement | Maximum |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Commercial Milestone Payments | $ 665,000 |  |  |  |  |  |  |

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