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v3.26.1

Organization and Nature of Business - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands |  |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Dec. 10, 2025 | Jun. 30, 2025 | Jul. 31, 2025 | Mar. 31, 2026 | Dec. 31, 2025 | Mar. 31, 2025
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  |  | $ 1,135,195 | $ 1,065,961 |
Cash, cash equivalents and marketable securities |  |  |  | $ 1,546,000 |  |
Common Stock Per Share Exercise Price |  |  |  | $ 0.0001 | $ 0.0001 |
Pre-funded warrants |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Pre-funded warrants outstanding |  |  |  | 15,815,253 |  | 15,159,753
Warrants exercised |  |  |  | 0 |  |
Increase or decrease pre-funded warrants, maximum |  |  |  | 19.99% |  |
Minimum pre-funded warrants, exercise |  |  |  | 4.99% |  |
Maximum pre-funded warrants, exercise |  |  |  | 9.99% |  |
Prior notice period, minimum |  |  |  | 61 days |  |
Common Stock | Pre-funded warrants |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Common Stock Per Share Exercise Price |  |  |  | $ 0.0001 |  |
Underwriters |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | 1,050,000 |  | 855,000 |  |  |
2025 Follow-on Public Offerings |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | 8,050,000 | 5,044,500 |  |  |  |
Common stock per share | $ 86 | $ 44 |  |  |  |
Aggregate Gross Proceeds | $ 692,300 | $ 250,800 | $ 288,400 |  |  |
2025 Follow-on Public Offerings | Pre-funded warrants |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Pre-funded warrant purchase price |  | $ 43.9999 |  |  |  |
2025 Follow-on Public Offerings | Common Stock | Pre-funded warrants |  |  |  |  |  |
Organization and Nature of Business [Line Items] |  |  |  |  |  |
Number of Common Stock Purchased in Place of Pre funded Warrants |  | 655,500 |  |  |  |
Common Stock Per Share Exercise Price |  | $ 0.0001 |  |  |  |

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