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Revenue Recognition - Additional Information (Details) - USD ($) $ in Thousands | 12 Months Ended |  |  |
--- | --- | --- | --- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023 | Mar. 24, 2023 | Dec. 31, 2022 | Feb. 25, 2022
Disaggregation of Revenue [Line Items] |  |  |  |  |  |
Milestone catch-up adjustment |  | $ 400 |  |  |  |
Revenue | $ 7,696 | 1,039 | $ 4,013 |  |  |
Loyal preferred stock value | 2,000 | 2,000 |  |  |  |
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa License |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |
Contract with customer, liability | 5,045 | 6,880 | 6,806 |  | $ 8,341 |
Milestone revenue |  | 1,000 |  |  |  |
Revenue recognized | 1,835 | 476 | 1,535 |  |  |
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa License | License |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |
Contract with customer, liability |  |  |  |  |  | $ 13,000
Additional milestone payments |  |  |  |  |  | 25,500
Transaction price | 14,000 | 14,000 |  |  |  | $ 13,000
Revenue recognized | 1,800 | 900 | 1,500 |  |  |
Revenue | 1,800 | 900 | 1,500 |  |  |
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa Clinical Supply Agreement | License |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |
Revenue | 400 | 100 | 400 |  |  |
Loyal | License |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |
Contract with customer, liability |  |  |  | $ 100 |  |
Revenue | $ 0 | $ 0 | $ 2,100 |  |  |
Preferred stock received, value |  |  |  | $ 2,000 |  |

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