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Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands | Total | Common Stock Shares | Common Stock and Paid-In Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit | Stock Held in Trust
--- | --- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2022 |  | 53,877,000 |  |  |  |
Beginning balance at Dec. 31, 2022 | $ 316,328 |  | $ 759,432 | $ (3,931) | $ (439,173) | $ 0
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |
Issuance of common stock, net of transaction costs (in shares) |  | 12,787,000 |  |  |  |
Issuance of common stock, net of transaction costs | 369,080 |  | 369,080 |  |  |
Exercise of stock options (in shares) |  | 1,283,000 |  |  |  |
Exercise of stock options | 20,091 |  | 20,091 |  |  |
Stock issued under Employee Stock Purchase Plan (in shares) |  | 147,000 |  |  |  |
Stock issued under Employee Stock Purchase Plan | 2,291 |  | 2,291 |  |  |
Issuance of common stock upon vesting of restricted stock units (in shares) |  | 81,000 |  |  |  |
Stock-based compensation | 40,937 |  | 40,937 |  |  |
Comprehensive income (loss) | 4,908 |  |  | 4,908 |  |
Net loss | (214,529) |  |  |  | (214,529) |
Ending balance (in shares) at Dec. 31, 2023 |  | 68,175,000 |  |  |  |
Ending balance at Dec. 31, 2023 | 539,106 |  | 1,191,831 | 977 | (653,702) | 0
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |
Issuance of common stock, net of transaction costs (in shares) |  | 21,986,000 |  |  |  |
Issuance of common stock, net of transaction costs | 970,048 |  | 970,048 |  |  |
Exercise of stock options (in shares) |  | 2,294,000 |  |  |  |
Exercise of stock options | 40,463 |  | 40,463 |  |  |
Stock issued under Employee Stock Purchase Plan (in shares) |  | 222,000 |  |  |  |
Stock issued under Employee Stock Purchase Plan | 4,224 |  | 4,224 |  |  |
Issuance of common stock upon vesting of restricted stock units (in shares) |  | 249,000 |  |  |  |
Stock-based compensation | 69,386 |  | 69,386 |  |  |
Comprehensive income (loss) | (14) |  |  | (14) |  |
Net loss | (298,408) |  |  |  | (298,408) |
Ending balance (in shares) at Dec. 31, 2024 |  | 92,926,000 |  |  |  |
Ending balance at Dec. 31, 2024 | $ 1,324,805 |  | 2,275,952 | 963 | (952,110) | 0
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |
Exercise of stock options (in shares) | 2,027,378 | 2,028,000 |  |  |  |
Exercise of stock options | $ 35,402 |  | 35,402 |  |  |
Stock issued under Employee Stock Purchase Plan (in shares) |  | 206,000 |  |  |  |
Stock issued under Employee Stock Purchase Plan | 5,219 |  | 5,219 |  |  |
Issuance of common stock upon vesting of restricted stock units (in shares) |  | 415,000 |  |  |  |
Stock-based compensation | 91,024 |  | 91,024 |  |  |
Stock held in trust under deferred compensation plan | 0 |  | 112 |  |  | (112)
Other | 48 |  | 48 |  |  |
Comprehensive income (loss) | 902 |  |  | 902 |  |
Net loss | (465,317) |  |  |  | (465,317) |
Ending balance (in shares) at Dec. 31, 2025 |  | 95,575,000 |  |  |  |
Ending balance at Dec. 31, 2025 | $ 992,083 |  | $ 2,407,757 | $ 1,865 | $ (1,417,427) | $ (112)

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