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Cover Page - USD ($)
$ in Billions
12 Months Ended
Dec. 31, 2025
Feb. 13, 2026
Jun. 30, 2025
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2025    
Current Fiscal Year End Date --12-31    
Document Transition Report false    
Entity File Number 001-38583    
Entity Registrant Name Crinetics Pharmaceuticals, Inc.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 26-3744114    
Entity Address, Address Line One 6055 Lusk Boulevard    
Entity Address, City or Town San Diego    
Entity Address, State or Province CA    
Entity Address, Postal Zip Code 92121    
City Area Code 858    
Local Phone Number 450-6464    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol CRNX    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction false    
Entity Shell Company false    
Entity Public Float     $ 2.7
Entity Common Stock, Shares Outstanding   104,705,330  
Documents Incorporated by Reference
Certain sections of the registrant’s definitive proxy statement for the 2026 annual meeting of stockholders to be filed with the Securities and Exchange Commission pursuant to Regulation 14A not later than 120 days after end of the fiscal year covered by this Annual Report on Form 10-K are incorporated by reference into Part III of this Annual Report on Form 10-K.
   
Entity Central Index Key 0001658247    
Document Fiscal Year Focus 2025    
Document Fiscal Period Focus FY    
Amendment Flag false