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Revenue Recognition - Additional Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023	Mar. 24, 2023	Dec. 31, 2022	Feb. 25, 2022
Disaggregation of Revenue [Line Items]
Milestone catch-up adjustment		$ 400
Revenue	$ 7,696	1,039	$ 4,013
Loyal preferred stock value	2,000	2,000
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa License
Disaggregation of Revenue [Line Items]
Contract with customer, liability	5,045	6,880	6,806		$ 8,341
Milestone revenue		1,000
Revenue recognized	1,835	476	1,535
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa License | License
Disaggregation of Revenue [Line Items]
Contract with customer, liability						$ 13,000
Additional milestone payments						25,500
Transaction price	14,000	14,000				$ 13,000
Revenue recognized	1,800	900	1,500
Revenue	1,800	900	1,500
Sanwa Kagaku Kenkyusho Co Ltd, Sanwa Clinical Supply Agreement | License
Disaggregation of Revenue [Line Items]
Revenue	400	100	400
Loyal | License
Disaggregation of Revenue [Line Items]
Contract with customer, liability				$ 100
Revenue	$ 0	$ 0	$ 2,100
Preferred stock received, value				$ 2,000

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