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Condensed Consolidated Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Operating expenses:        
Research and development $ 5,561 $ 3,158 $ 16,882 $ 7,638
General and administrative 1,577 863 4,387 2,155
Total operating expenses 7,138 4,021 21,269 9,793
Loss from operations (7,138) (4,021) (21,269) (9,793)
Interest income 54 1 93 2
Change in fair value of redeemable convertible preferred stock tranche and warrant liabilities   571 (4,719) 426
Other expense     (34)  
Net loss (7,084) (3,449) (25,929) (9,365)
Net loss attributable to common stockholders $ (7,377) $ (3,485) $ (26,487) $ (9,401)
Net loss per share attributable to common stockholders, basic and diluted $ (0.87) $ (12.79) $ (8.62) $ (38.32)
Weighted-average shares used to compute net loss per share attributable to common stockholders, basic and diluted 8,483,189 272,409 3,071,456 245,298