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Equity Plans | 3 Months Ended
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Mar. 31, 2020
Equity Plans |
Equity Plans | Note 11. Equity Plans Equity Incentive Plan In July 2016, the Company’s board of directors and stockholders approved the Company’s 2016 Equity Incentive Plan (the “2016 Plan”) to replace the 2007 Stock Option Plan. The 2016 Plan is administered by the board of directors or a committee appointed by the board of directors, which determines the types of awards to be granted, including the number of shares subject to the awards, the exercise price and the vesting schedule. Awards granted under the 2016 Plan expire no later than ten years from the date of grant. As of March 31, 2020, 632,901 shares were available for issuance under the 2016 Plan. Inducement Plan In May 2018, the Company’s board of directors approved the 2018 Inducement Plan, a non-stockholder approved stock plan, under which it reserved and authorized up to 750,000 shares of the Company’s common stock in order to award options and restricted stock unit awards to persons that were not previously employees or directors of the Company, or following a bona fide period of non-employment, as an inducement material to such persons entering into employment with the Company, within the meaning of Rule 5635(c)(4) of the NASDAQ Listing Rules. The 2018 Inducement Plan is administered by the board of directors or the Compensation Committee of the board, which determines the types of awards to be granted, including the number of shares subject to the awards, the exercise price and the vesting schedule. Awards granted under the 2018 Inducement Plan expire no later than ten years from the date of grant. On February 18, 2020, the Compensation Committee of the board approved the amendment and restatement of the 2018 Inducement Plan (the “Amended and Restated Inducement Plan”) to provide for the reservation of an additional 500,000 shares of the Company’s common stock for issuance under the Amended and Restated Inducement Plan. As of March 31, 2020, 780,000 shares were available for issuance under the Amended and Restated Inducement Plan. Stock Options Stock option activity under the Company’s equity incentive and inducement plans is set forth below:
|  |  |  | Weighted- |  | Weighted- |  |
|  |  |  | Average |  | Average |  |
|  |  |  | Exercise |  | Remaining |  | Aggregate
|  | Options |  | Price Per |  | Contractual |  | Intrinsic
|  | Outstanding |  | Share |  | Life (years) |  | Value (1)
|  |  |  |  |  |  |  |  | (in millions)
Balances at December 31, 2019 |  | 3,681,521 |  | $ | 11.64 |  | 7.78 |  |  |
Options granted |  | 977,600 |  |  | 7.78 |  |  |  |  |
Options exercised |  | (29,167) |  |  | 1.50 |  |  |  |  |
Options forfeited |  | (52,367) |  |  | 11.85 |  |  |  |  |
Balances at March 31, 2020 |  | 4,577,587 |  | $ | 10.87 |  | 8.06 |  | $ | 2.2
Options exercisable – March 31, 2020 |  | 2,167,161 |  | $ | 11.90 |  | 6.84 |  | $ | 2.2
Options vested and expected to vest – March 31, 2020 |  | 4,577,587 |  | $ | 10.87 |  | 8.06 |  | $ | 2.2
| (1) |  | The aggregate intrinsic values were calculated as the difference between the exercise price of the options and the closing price of the Company’s common stock on March 31, 2020. The calculation excludes options with an exercise price higher than the closing price of the Company’s common stock on March 31, 2020.
During the three months ended March 31, 2020, the estimated weighted-average grant-date fair value of common stock underlying options granted to employees was $5.01 per share. Stock Options Valuation Assumptions The fair value of employee stock option awards was estimated at the date of grant using a Black-Scholes option-pricing model with the following assumptions:
|  | Three Months Ended March 31,
|  | 2020 |  | 2019
Expected term (in years) |  | 5.27 - 6.08 |  | 6.02 - 6.08
Expected volatility |  | 72.1% - 73.8% |  | 62.2% - 62.6%
Risk-free interest rate |  | 0.59% - 1.44% |  | 2.45% - 2.58%
Dividend yield |  | — |  | —
In determining the fair value of the options granted, the Company uses the Black-Scholes option-pricing model and assumptions discussed below. Each of these inputs is subjective, and expected volatility generally requires significant judgment to determine. Expected Term—The Company’s expected term represents the period that the Company’s options granted are expected to be outstanding and is determined using the simplified method (based on the mid-point between the vesting date and the end of the contractual term). The Company has limited historical information to develop reasonable expectations about future exercise patterns and post-vesting employment termination behavior for its stock option grants. Expected Volatility— Prior to January 1, 2020, the Company’s expected volatility was estimated based on the average volatility for comparable publicly traded biopharmaceutical companies over a period equal to the expected term of the stock option grants. Beginning January 1, 2020, the Company’s expected volatility was estimated based upon a mix of 75% of the average volatility for comparable publicly traded biopharmaceutical companies over a period equal to the expected term of the stock option grants and 25% of the volatility of the Company’s stock price since its initial public offering in August 2016. Risk-Free Interest Rate—The risk-free interest rate is based on the U.S. Treasury zero coupon issues in effect at the time of grant for periods corresponding with the expected term of option. Expected Dividend—The Company has never paid dividends on its common stock and has no plans to pay dividends on its common stock. Therefore, the Company used an expected dividend yield of zero. Restricted Stock Units Restricted stock unit activity under the Company’s equity incentive plans is set forth below:
|  |  |  | Weighted
|  |  |  | Average
|  | Number of |  | Grant Date
|  | Shares |  | Fair Value
Unvested at December 31, 2019 |  | 278,482 |  | $ | 10.08
Granted |  | 142,000 |  |  | 7.80
Vested |  | (131,147) |  |  | 9.52
Forfeited |  | (9,338) |  |  | 9.35
Unvested at March 31, 2020 |  | 279,997 |  | $ | 9.21
Employee Stock Purchase Plan The 2016 Employee Stock Purchase Plan (“2016 ESPP”) allows eligible employees to purchase shares of the Company’s common stock at a discount through payroll deductions of up to 15% of their eligible compensation. At the end of each offering period, eligible employees are able to purchase shares at 85% of the lower of the fair market value of the Company’s common stock at the beginning of the offering period or at the end of each applicable purchase period. During the three months ended March 31, 2020, a total of 56,742 shares of common stock were issued under the 2016 ESPP, and 793,427 shares remain available for issuance. Stock-Based Compensation Total stock-based compensation expense was as follows (in thousands):
|  | Three Months Ended March 31,
|  | 2020 |  | 2019
Research and development |  | $ | 1,066 |  | $ | 1,122
General and administrative |  |  | 982 |  |  | 857
Total stock-based compensation expense |  | $ | 2,048 |  | $ | 1,979
As of March 31, 2020, total unrecognized stock-based compensation expense was approximately $16.2 million, which the Company expects to recognize over a weighted-average period of approximately 3.1 years.

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