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v3.20.4

Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2020
Income Taxes |
Schedule of domestic and foreign components of net loss | The following table presents domestic and foreign components of net loss before income taxes (in thousands):
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ |  | 2020 |  | 2019 |  | 2018
Domestic | ​ | $ | (71,073) | ​ | $ | (72,271) |  | $ | (37,511)
Foreign | ​ |  | 6,228 | ​ |  | (5,607) |  |  | (2,212)
Total net loss before taxes | ​ | $ | (64,845) | ​ | $ | (77,878) |  | $ | (39,723)
Schedule of federal, state and foreign of the income tax expense (benefit) | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ | ​ | 2020 | ​ | 2019 | ​ | 2018
Current: | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Federal | ​ | $ | — | ​ | $ | — | ​ | $ | —
State | ​ | ​ | — | ​ | ​ | — | ​ | ​ | —
Foreign | ​ | ​ | (88) | ​ | ​ | 84 | ​ | ​ | —
Total current tax (benefit) expense | ​ | ​ | (88) | ​ | ​ | 84 | ​ | ​ | —
Deferred: | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Federal | ​ | ​ | — | ​ | ​ | — | ​ | ​ | —
State | ​ | ​ | — | ​ | ​ | — | ​ | ​ | —
Foreign | ​ | ​ | 1,393 | ​ | ​ | (775) | ​ | ​ | (799)
Total deferred tax expense (benefit) | ​ | ​ | 1,393 | ​ | ​ | (775) | ​ | ​ | (799)
Total income tax expense (benefit) | ​ | $ | 1,305 | ​ | $ | (691) | ​ | $ | (799)
Schedule of provision differences from federal statutory rate | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31, |
​ |  | 2020 |  | 2019 |  | 2018 |
Federal statutory income tax rate |  | 21.0 | % | 21.0 | % | 21.0 | %
State taxes, net of federal benefit |  | 1.9 |  | 1.2 |  | 7.0 |
Research and development credits | ​ | 6.5 | ​ | 4.3 | ​ | (1.3) | ​
Foreign tax rate difference |  | (0.9) |  | 0.7 |  | 0.4 |
Change in valuation allowance |  | (34.3) |  | (23.8) |  | (22.2) |
Other |  | 3.8 |  | (2.5) |  | (2.9) |
Provision (benefit) for income taxes |  | (2.0) | % | 0.9 | % | 2.0 | %
Schedule of components of deferred tax assets | The components of the deferred tax assets are as follows (in thousands):
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31,
​ |  | 2020 |  | 2019
Deferred tax assets: | ​ | ​ | ​ |  | ​ | ​
Net operating loss carryforwards | ​ | $ | 50,272 | ​ | $ | 39,907
Depreciation and amortization | ​ |  | 1,237 | ​ |  | 318
Accruals/other | ​ |  | 5,332 | ​ |  | 5,454
Operating lease liability | ​ | ​ | 1,252 | ​ | ​ | 1,516
Research and development and foreign credits | ​ |  | 14,856 | ​ |  | 8,038
Total deferred tax assets | ​ |  | 72,949 | ​ |  | 55,233
Deferred tax liabilities: | ​ | ​ | ​ | ​ | ​ | ​
Operating right-of-use asset | ​ | ​ | (1,040) | ​ | ​ | (1,269)
Total deferred tax liabilities | ​ | ​ | (1,040) | ​ | ​ | (1,269)
Valuation allowance | ​ |  | (71,909) | ​ |  | (52,531)
Net deferred tax assets | ​ | $ | — | ​ | $ | 1,433
​
Schedule of reconciliation of beginning and ending unrecognized tax benefits | A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands):
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ |  | 2020 |  | 2019 |  | 2018
Balance at beginning of year | ​ | $ | 16,631 | ​ | $ | 9,466 |  | $ | 5,414
(Decreases) increases based on tax positions related to prior years | ​ |  | (3,799) | ​ |  | 184 |  |  | 108
Increases based on tax positions related to current year | ​ |  | 7,053 | ​ |  | 6,981 |  |  | 3,944
Balance at end of year | ​ | $ | 19,885 | ​ | $ | 16,631 |  | $ | 9,466

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