    <SEC-DOCUMENT>0001104659-21-050202-index.html : 20210414
    <SEC-HEADER>0001104659-21-050202.hdr.sgml : 20210414
    <ACCEPTANCE-DATETIME>20210414160843
    ACCESSION NUMBER:		0001104659-21-050202
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20210527
    FILED AS OF DATE:		20210414
    DATE AS OF CHANGE:		20210414

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Protagonist Therapeutics, Inc
    		CENTRAL INDEX KEY:			0001377121
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				980505495
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37852
    		FILM NUMBER:		21825804

    	BUSINESS ADDRESS:
    		STREET 1:		7707 GATEWAY BLVD., SUITE 140
    		CITY:			NEWARK
    		STATE:			CA
    		ZIP:			94560-1160
    		BUSINESS PHONE:		(510) 474-0170

    	MAIL ADDRESS:
    		STREET 1:		7707 GATEWAY BLVD., SUITE 140
    		CITY:			NEWARK
    		STATE:			CA
    		ZIP:			94560-1160

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Protagonist Therapeutics Inc
    		DATE OF NAME CHANGE:	20130605

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Protagonist Inc
    		DATE OF NAME CHANGE:	20061002
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>tm212463-1_def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: tm212463-1_def14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_protagonist-pn.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_protagonist-pn.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm212463d1-proxy_protapg1bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm212463d1-proxy_protapg1bw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm212463d1-proxy_protapg2bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm212463d1-proxy_protapg2bw.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>