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Cash Equivalents and Marketable Securities - Cash Equivalents and Marketable Securities (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	$ 299,915	$ 318,713
Total cash equivalents and marketable securities, Gross Unrealized Gains	2
Total cash equivalents and marketable securities, Gross Unrealized Losses	(413)	(143)
Total cash equivalents and marketable securities, Fair Value	299,504	318,570
U.S. Treasury and agency securities
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	77,915	40,093
Total cash equivalents and marketable securities, Gross Unrealized Gains	1
Total cash equivalents and marketable securities, Gross Unrealized Losses	(268)	(76)
Total cash equivalents and marketable securities, Fair Value	77,648	40,017
Corporate debt securities
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	45,455	75,598
Total cash equivalents and marketable securities, Gross Unrealized Losses	(105)	(50)
Total cash equivalents and marketable securities, Fair Value	45,350	75,548
Supranational and sovereign government securities
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	3,000	6,011
Total cash equivalents and marketable securities, Gross Unrealized Losses		(1)
Total cash equivalents and marketable securities, Fair Value	3,000	6,010
Money Market Funds
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	35,422	39,854
Total cash equivalents and marketable securities, Fair Value	35,422	39,854
Commercial Paper
Cash Equivalents and Marketable Securities
Total cash equivalents and marketable securities, Amortized Cost	138,123	157,157
Total cash equivalents and marketable securities, Gross Unrealized Gains	1
Total cash equivalents and marketable securities, Gross Unrealized Losses	(40)	(16)
Total cash equivalents and marketable securities, Fair Value	$ 138,084	$ 157,141

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This item represents the cost of debt and equity securities, including cash equivalents which are categorized neither as held-to-maturity nor trading, net of adjustments including accretion, amortization, collection of cash, previous other-than-temporary impairments recognized in earnings (less any cumulative-effect adjustments recognized, as defined), and fair value hedge accounting adjustments, if any.

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The aggregate fair value of amount of investment in debt and equity securities and cash equivalents categorized neither as held-to-maturity nor trading.

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Amount of unrealized gain before deducting unrealized loss on investments in debt and equity securities classified as cash equivalents and marketable securities.

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Amount of unrealized loss before deducting unrealized gain on investments in cash equivalents and marketable securities.

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