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Research Collaboration and License Agreement (Details)	3 Months Ended		12 Months Ended
	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)	Dec. 31, 2014 USD ($) payment
Research Collaboration and License Agreement
Research and development	$ 36,318,000	$ 24,245,000
Research Collaboration and License Agreement | Zealand Pharma
Research Collaboration and License Agreement
Aggregate milestone payment			$ 1,000,000.0
Number of development milestone payments | payment			3
Research and development	$ 0	$ 0

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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