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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended 3 Months Ended
Nov. 27, 2019
Jan. 31, 2022
Jun. 30, 2021
Oct. 31, 2019
Dec. 31, 2018
Aug. 31, 2018
Mar. 31, 2022
Dec. 31, 2021
Aug. 06, 2018
Stock transactions                  
Par value (per share)             $ 0.00001 $ 0.00001  
2019 Form S-3                  
Stock transactions                  
Common stock available for sale             $ 79.3    
Maximum aggregate offering price       $ 250.0          
2019 Sales Agreement                  
Stock transactions                  
Common stock issued (in shares)   422,367              
Common stock available for sale             $ 17.0    
Maximum aggregate offering price $ 250.0     $ 75.0          
Proceeds from public offering of common stock, net of issuance costs   $ 14.6              
Underwritten public offering                  
Stock transactions                  
Net proceeds from sale of common stock     $ 123.8            
Common stock issued (in shares)     3,046,358            
Common stock issued, price per share     $ 37.75            
underwritten public offering, Additional offering                  
Stock transactions                  
Common stock issued (in shares)     456,953            
Common stock issued, price per share     $ 37.75            
Common Stock                  
Stock transactions                  
Common stock issued (in shares)             422,367    
Common Stock | Private Placement                  
Stock transactions                  
Number of warrants exercised             0    
Investors | Private Placement                  
Stock transactions                  
Aggregate shares of common stock sold           2,750,000      
Common stock sold, price per share           $ 8.00      
Net proceeds from sale of common stock           $ 21.7      
Warrants issued to purchase common stock, number of shares                 2,750,000
Warrants exercisable date           Aug. 08, 2023      
Exchange Agreement | Exchanging Stockholders                  
Stock transactions                  
Warrants issued to purchase common stock, number of shares         1,000,000        
Exercise Price (per share)         $ 0.00001        
Common stock exchanged for pre-funded warrants         1,000,000        
Par value (per share)         $ 0.00001        
Duration of warrants from date of issuance (in years)         10 years        
Equity method investment, ownership percentage         9.99%        
Exchange Agreement | Exchanging Stockholders | Common Stock                  
Stock transactions                  
Remaining number of Exchange Warrants unexercised             400,000    
$10.00 per share | Investors | Private Placement                  
Stock transactions                  
Warrants to purchase common stock (in shares)                 1,375,000
Exercise Price (per share)                 $ 10.00
$15.00 per share | Investors | Private Placement                  
Stock transactions                  
Warrants to purchase common stock (in shares)                 1,375,000
Exercise Price (per share)                 $ 15.00