<SEC-DOCUMENT>0001104659-22-086733-index.html : 20220805
<SEC-HEADER>0001104659-22-086733.hdr.sgml : 20220805
<ACCEPTANCE-DATETIME>20220805163355
ACCESSION NUMBER:		0001104659-22-086733
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		14
FILED AS OF DATE:		20220805
DATE AS OF CHANGE:		20220805

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Protagonist Therapeutics, Inc
		CENTRAL INDEX KEY:			0001377121
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				980505495
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-266595
		FILM NUMBER:		221141360

	BUSINESS ADDRESS:	
		STREET 1:		7707 GATEWAY BLVD., SUITE 140
		CITY:			NEWARK
		STATE:			CA
		ZIP:			94560-1160
		BUSINESS PHONE:		(510) 474-0170

	MAIL ADDRESS:	
		STREET 1:		7707 GATEWAY BLVD., SUITE 140
		CITY:			NEWARK
		STATE:			CA
		ZIP:			94560-1160

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Protagonist Therapeutics Inc
		DATE OF NAME CHANGE:	20130605

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Protagonist Inc
		DATE OF NAME CHANGE:	20061002
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>tm2222499-1_s3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: tm2222499-1_s3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.2
<SEQUENCE>2
<FILENAME>tm2222499d2_ex1-2.htm
<DESCRIPTION>EXHIBIT 1.2
<TEXT>
Document 2 - file: tm2222499d2_ex1-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.2
<SEQUENCE>3
<FILENAME>tm2222499d2_ex4-2.htm
<DESCRIPTION>EXHIBIT 4.2
<TEXT>
Document 3 - file: tm2222499d2_ex4-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.3
<SEQUENCE>4
<FILENAME>tm2222499d2_ex4-3.htm
<DESCRIPTION>EXHIBIT 4.3
<TEXT>
Document 4 - file: tm2222499d2_ex4-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>5
<FILENAME>tm2222499d2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 5 - file: tm2222499d2_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.2
<SEQUENCE>6
<FILENAME>tm2222499d2_ex5-2.htm
<DESCRIPTION>EXHIBIT 5.2
<TEXT>
Document 6 - file: tm2222499d2_ex5-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>7
<FILENAME>tm2222499d2_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 7 - file: tm2222499d2_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>8
<FILENAME>tm2222499d2_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
Document 8 - file: tm2222499d2_ex23-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>9
<FILENAME>tm2222499d2_exfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 9 - file: tm2222499d2_exfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>tm2222499d2_ex5-2img001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: tm2222499d2_ex5-2img001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tm2222499d2_ex5-2img002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tm2222499d2_ex5-2img002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>tm2222499d2_ex5-1img001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: tm2222499d2_ex5-1img001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>tm2222499d2_ex5-1img002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: tm2222499d2_ex5-1img002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>lg_protagonist-pn.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: lg_protagonist-pn.jpg

</DOCUMENT>
</SEC-DOCUMENT>