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Commitments and contingencies (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Oct. 01, 2019
Aug. 15, 2018
Jun. 30, 2019
Jun. 30, 2019
Commitments and contingencies        
Non cancellation period for use and occupancy agreement   9 months    
Written notice for cancellation of agreement   60 days    
Base rental expense for the office space   $ 12    
Monthly lease payments payable under the amended agreement $ 19      
Increase in rental expense (as a percentage) 3.00%      
Security deposit     $ 20 $ 20
Rent expense     89 138
Non-cancelable purchase commitments with contract research organizations and contract manufacturing organizations     $ 5,172 $ 5,172