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Commitments and contingencies (Details) $ in Thousands | Mar. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Jul. 10, 2020 ft² | Feb. 29, 2020 USD ($)
--- | --- | --- | --- | ---
Commitments and contingencies |  |  |  |
Lease agreement term |  |  |  | 7 years
Square feet of office | ft² |  |  | 6,647 |
Minimum payments during the term |  |  |  | $ 2,300
Non-cancelable purchase commitments with contract research organizations and contract manufacturing organizations | $ 11,153 |  |  |
Total lease liability | $ 1,655 |  |  |
Operating Lease, Liability, Statement of Financial Position [Extensible List] | us-gaap:PrepaidExpenseAndOtherAssetsCurrent us-gaap:OperatingLeaseLiabilityNoncurrent |  |  |
Operating lease liability, noncurrent | $ 1,467 | $ 1,516 |  |
Short-term Liabilities | $ 188 |  |  |
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] | Prepaid Expense and Other Assets, Current |  |  |

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- Definition Area of land subject to a ground lease. + References No definition available. + Details
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- Definition Term of lessor's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 30 -Section 50 -Paragraph 3 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=121576215&loc=SL77919359-209981 + Details
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- Definition Present value of lessee's discounted obligation for lease payments from operating lease. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 45 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=121603541&loc=SL77918627-209977 + Details
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- Definition Present value of lessee's discounted obligation for lease payments from operating lease, classified as current. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 45 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=121603541&loc=SL77918627-209977 + Details
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