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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (15,090) $ (11,886)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 2,364 1,237
Depreciation 11  
Non-cash lease expense 50 54
Net amortization of premiums and discounts on short-term investments 121 (103)
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (2,787) 724
Accounts payable 1,177 588
Accrued expenses and other current liabilities (4,143) (1,877)
Operating lease liability (49) (54)
Net cash used in operating activities (18,346) (11,317)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchase of short-term marketable securities   (24,781)
Proceeds from maturities of short-term marketable securities 19,000 18,500
Net cash provided by (used in) investing activities 19,000 (6,281)
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from the exercise of stock options 24 112
Proceeds from the disgorgement of stockholders' short-swing profits, net   52
Net cash provided by financing activities 24 164
Net increase (decrease) in cash, cash equivalents and restricted cash 678 (17,434)
Cash, cash equivalents and restricted cash at the beginning of the period 187,390 64,848
Cash, cash equivalents and restricted cash at the end of the period 188,068 47,414
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING INFORMATION:    
Net unrealizable gain (loss) on marketable securities $ 1 $ 51