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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (68,353) $ (49,496)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 7,412 4,106
Depreciation 30 6
Non-cash lease expense 151 147
Net amortization of premiums and discounts on short-term investments 705 (41)
Unrealized foreign exchange gain and loss (113)  
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (3,229) (4,539)
Accounts payable 3,469 3,689
Accrued expenses and other current liabilities 7,076 (1,183)
Other liabilities   (2)
Operating lease liability (134) (96)
Net cash used in operating activities (52,986) (47,409)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchase of short-term marketable securities (43,561) (106,041)
Proceeds from sales of short-term marketable securities   9,864
Proceeds from maturities of short-term marketable securities 73,841 68,660
Purchase of property and equipment   (143)
Net cash provided by (used in) investing activities 30,280 (27,660)
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from the issuance of common stock in follow-on public offering, net of issuance costs and underwriting fees   202,554
Proceeds from the exercise of stock options 636 284
Proceeds from the issuance of common stock pursuant to employee stock purchase plan purchases 215 158
Proceeds from the disgorgement of stockholders' short-swing profits, net   52
Payment of deferred offering costs (492)  
Net cash provided by financing activities 359 203,048
Net (decrease) increase in cash, cash equivalents and restricted cash (22,347) 127,979
Cash, cash equivalents and restricted cash at the beginning of the period 187,390 64,848
Cash, cash equivalents and restricted cash at the end of the period 165,043 192,827
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING INFORMATION:    
ROU asset obtained in exchange for operating lease liability   1,751
Change in net unrealizable gain (loss) on marketable securities (14) 22
Remeasurement of ROU asset and lease liability   $ 173
Deferred offering costs included in accounts payable and accrued expenses and other current liabilities $ 4