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Financial Statements Schedule I - Condensed Statements of Cash Flows (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Cash flows from Operating activities: |  |  |
Net loss | $ (50,384,176) | $ (37,512,212) | $ (18,021,737)
Adjustments to reconcile net loss to net cash provided by operating activities: |  |  |
Share-based compensation | 9,931,106 | 4,925,278 | 2,701,404
Change in fair value of warrants | (200,000) | 1,920,000 | 1,980,000
Share of loss from equity method investment | 249,652 |  |
Changes in operating assets and liabilities: |  |  |
Prepayments and other current assets | (810,979) | (74,507) | 33,713
Other payables | 1,950,152 | 242,187 | 327,500
Deferred income | 1,615,690 | 716,835 | 61,599
Net cash used in operating activities | (32,367,181) | (32,158,031) | (11,464,910)
Cash flows from investing activities: |  |  |
Net cash used in investing activities | (10,434,231) | (2,729,497) | (738,470)
Cash flows from financing activities: |  |  |
Proceed from issuance of convertible preferred shares, net of issuance cost | 29,100,000 | 106,200,000 | 18,278,572
Proceeds from exercise of warrants | 1,000,000 |  |
Proceeds from exercises of stock options | 65,500 |  |
Proceeds from issuance of ordinary shares upon initial public offering | 160,424,994 |  |
Payment of initial public offering costs | (2,730,299) |  |
Net cash provided by financing activities | 187,860,195 | 106,200,000 | 18,278,572
Effect of foreign exchange rate changes on cash and cash equivalents | 652,595 | (524,398) | (66,770)
Net increases in cash and cash equivalents | 145,711,378 | 70,788,074 | 6,008,422
Cash and cash equivalents - beginning of the year | 83,948,770 | 13,160,696 | 7,152,274
Cash and cash equivalents - end of the year | 229,660,148 | 83,948,770 | 13,160,696
Parent Company |  |  |
Cash flows from Operating activities: |  |  |
Net loss | (50,384,176) | (37,512,212) | (18,021,737)
Adjustments to reconcile net loss to net cash provided by operating activities: |  |  |
Share-based compensation | 3,346,039 | 534,660 | 56,806
Change in fair value of warrants | (200,000) | 1,920,000 | 1,980,000
Share of loss from equity method investment | 46,598,092 | 35,057,552 | 15,984,931
Changes in operating assets and liabilities: |  |  |
Prepayments and other current assets | (450,333) |  |
Other payables | 553,317 |  |
Deferred income | 1,482,000 |  |
Net cash used in operating activities | 944,939 |  |
Cash flows from investing activities: |  |  |
Investment in subsidiaries | (31,707,566) | (84,501,020) | (21,500,000)
Net cash used in investing activities | (31,707,566) | (84,501,020) | (21,500,000)
Cash flows from financing activities: |  |  |
Proceed from issuance of convertible preferred shares, net of issuance cost | 29,100,000 | 106,200,000 | 18,278,572
Proceeds from exercise of warrants | 1,000,000 |  |
Proceeds from exercises of stock options | 65,500 |  |
Proceeds from issuance of ordinary shares upon initial public offering | 160,424,994 |  |
Payment of initial public offering costs | (2,730,299) |  |
Net cash provided by financing activities | 187,860,195 | 106,200,000 | 18,278,572
Net increases in cash and cash equivalents | 157,097,568 | 21,698,980 | (3,221,428)
Cash and cash equivalents - beginning of the year | 24,813,050 | 3,114,070 | 6,335,498
Cash and cash equivalents - end of the year | $ 181,910,618 | $ 24,813,050 | $ 3,114,070

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