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Loss per share
6 Months Ended
Jun. 30, 2021
Loss per share  
Loss per share
12. Loss per share
Basic and diluted net loss per share for each of the period presented are calculated as follows:
 
    
Three Months Ended June 30,
    
Six Months Ended June 30,
 
    
2021
    
2020
    
2021
    
2020
 
    
            $            
    
            $            
    
            $            
    
            $            
 
Numerator:
                                   
Net loss attributable to ordinary shareholders
     (163,324      (80,629      (396,234      (128,617
Denominator:
                                   
Weighted average number of ordinary shares- basic and diluted
     93,045,531        74,738,563        90,723,132        73,847,551  
    
 
 
    
 
 
    
 
 
    
 
 
 
Product revenue - net
     (1.76      (1.08      (4.37      (1.74
    
 
 
    
 
 
    
 
 
    
 
 
 
As a result of the Group’s net loss for the six months ended June 30, 2021 and 2020, share options and
non-vested
restricted shares outstanding in the respective periods were excluded from the calculation of diluted loss per share as their inclusion would have been anti-dilutive.
 
    
As of
 
    
June 30,

2021
    
June 30,

2020
 
Share options
     8,629,440        9,808,561  
Non-vested
restricted shares
     632,535        710,068