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Consolidated statements of operations - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Income Statement [Abstract]        
Revenue $ 36,935 $ 10,995 $ 57,038 $ 19,213
Expenses:        
Cost of sales (10,868) (2,896) (18,373) (4,980)
Research and development (142,224) (68,307) (346,076) (102,049)
Selling, general and administrative (54,414) (23,758) (90,252) (42,472)
Loss from operations (170,571) (83,966) (397,663) (130,288)
Interest income 244 1,227 458 2,882
Interest expenses   (55)   (114)
Other income (expense), net 7,406 2,434 1,179 (691)
Loss before income tax and share of loss from equity method investment (162,921) (80,360) (396,026) (128,211)
Income tax expense    
Share of loss from equity method investment (403) (269) (208) (406)
Net loss (163,324) (80,629) (396,234) (128,617)
Net loss attributable to ordinary shareholders $ (163,324) $ (80,629) $ (396,234) $ (128,617)
Loss per share - basic and diluted $ (1.76) $ (1.08) $ (4.37) $ (1.74)
Weighted-average shares used in calculating net loss per ordinary share - basic and diluted 93,045,531 74,738,563 90,723,132 73,847,551