<SEC-DOCUMENT>0000904454-22-000409.txt : 20220803
<SEC-HEADER>0000904454-22-000409.hdr.sgml : 20220803
<ACCEPTANCE-DATETIME>20220803172208
ACCESSION NUMBER:		0000904454-22-000409
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20220801
FILED AS OF DATE:		20220803
DATE AS OF CHANGE:		20220803

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Smiley Joshua L
		CENTRAL INDEX KEY:			0001725189

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38205
		FILM NUMBER:		221133719

	MAIL ADDRESS:	
		STREET 1:		LILLY CORPORATE CENTER
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46285

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Zai Lab Ltd
		CENTRAL INDEX KEY:			0001704292
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4560 JINKE ROAD
		STREET 2:		BLDG. 1, 4F, PUDONG
		CITY:			SHANGHAI
		STATE:			F4
		ZIP:			201210
		BUSINESS PHONE:		862161632588

	MAIL ADDRESS:	
		STREET 1:		4560 JINKE ROAD
		STREET 2:		BLDG. 1, 4F, PUDONG
		CITY:			SHANGHAI
		STATE:			F4
		ZIP:			201210
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>ownership.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-08-01</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001704292</issuerCik>
        <issuerName>Zai Lab Ltd</issuerName>
        <issuerTradingSymbol>ZLAB</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001725189</rptOwnerCik>
            <rptOwnerName>Smiley Joshua L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ZAI LAB LIMITED</rptOwnerStreet1>
            <rptOwnerStreet2>314 MAIN STREET, 4TH FLOOR, SUITE 100</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Operating Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Bruce Blefeld, Attorney-in-Fact</signatureName>
        <signatureDate>2022-08-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
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</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>poa_smiley-080122.htm
<DESCRIPTION>POWER OF ATTORNEY BY JOSHUA L SMILEY RE ZAI LAB LTD
<TEXT>
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  <div>
    <div style="text-align: center; font-weight: bold;"> <br>
    </div>
    <div style="text-align: center; font-weight: bold;">LIMITED POWER OF ATTORNEY</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">The undersigned hereby constitutes and appoints F. Ty Edmondson and Bruce Blefeld, and each of them individually, with full power of substitution, as the undersigned&#8217;s true and lawful
      attorney-in-fact to:</div>
    <div><br>
    </div>
    <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" id="z8066639c570e4d19919c33a4906665a3" cellpadding="0" cellspacing="0">

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          <td style="width: 36pt;"><br>
          </td>
          <td style="width: 36pt; vertical-align: top; align: right;">(1)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>prepare, execute in the undersigned&#8217;s name and on the undersigned&#8217;s behalf, and submit to the U.S. Securities and Exchange Commission (the &#8220;SEC&#8221;) a Form ID, including amendments thereto, and any other documents necessary or appropriate to
              obtain codes and passwords enabling the undersigned to make electronic filings with the SEC of reports required by Section 16(a) of the Securities Exchange Act of 1934, as amended, or any rule or regulation of the SEC;</div>
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          <td style="width: 36pt; vertical-align: top; align: right;">(2)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">
            <div>execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as officer and/or director of Zai Lab Limited (the &#8220;Company&#8221;), Forms&#160;3, 4, 5 and any Schedules 13D or 13G in accordance with Section&#160;16(a) of the Securities
              Exchange Act of 1934, as amended, and the rules thereunder;</div>
          </td>
        </tr>

    </table>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: -36pt; margin-left: 72pt;"><font class="HorizontalTab" style="width: 9pt; font-size: 1px; display: inline-block;">&#160;</font><br>
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          <td style="width: 36pt; vertical-align: top; align: right;">(3)</td>
          <td style="width: auto; vertical-align: top; text-align: justify;">do and perform any and all acts for and on behalf of the undersigned that may be necessary or desirable to complete and execute any such Form&#160;3, 4, or 5 or Schedule 13D or 13G,
            complete and execute any amendment or amendments thereto, and timely file such form with the SEC and any stock exchange or similar authority; and </td>
        </tr>

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    <div><br>
    </div>
    <div>
      <table style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000;" class="DSPFListTable" cellpadding="0" cellspacing="0">

          <tr>
            <td style="width: 36pt;"><br>
            </td>
            <td style="width: 36pt; vertical-align: top; align: right;">(4)</td>
            <td style="width: auto; vertical-align: top; text-align: justify;">
              <div>take any other action of any type whatsoever in connection with the foregoing that, in the opinion of each such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood
                that the documents executed by each such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as each such attorney-in-fact may approve in each
                such attorney-in-fact&#8217;s discretion.</div>
            </td>
          </tr>

      </table>
    </div>
    <div style="text-align: justify; text-indent: 36pt;"> <br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the
      exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that each
      such attorney-in-fact, or each such attorney-in-fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted.&#160; The undersigned acknowledges that each foregoing
      attorney-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned&#8217;s responsibilities to comply with Section&#160;16 of the Securities Exchange Act of 1934, as amended.</div>
    <div><br>
    </div>
    <div style="text-align: justify; text-indent: 36pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms&#160;3, 4, 5, and any Schedules 13D or 13G with respect to the undersigned&#8217;s holdings
      of and transactions in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to each foregoing attorney-in-fact.</div>
    <div><br>
    </div>
    <div style="text-align: center; text-indent: 36pt;">[<font style="font-style: italic;">Remainder of page intentionally left blank</font>]</div>
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    <div style="text-align: justify; text-indent: 36pt;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 3rd day of August, 2022.</div>
    <div><br>
    </div>
    <div><br>
    </div>
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          <td style="vertical-align: top; width: 33.33%; padding-bottom: 2px;">&#160;</td>
          <td style="vertical-align: top; width: 50.36%; border-bottom: 2px solid rgb(0, 0, 0);">
            <div style="text-align: justify;">/s/ Joshua L Smiley</div>
          </td>
          <td style="vertical-align: top; width: 16.31%; padding-bottom: 2px;">&#160;</td>
        </tr>
        <tr>
          <td style="vertical-align: top; width: 33.33%;">&#160;</td>
          <td style="vertical-align: top; width: 50.36%;">
            <div style="text-align: justify;">Name:&#160; Joshua L Smiley</div>
          </td>
          <td style="vertical-align: top; width: 16.31%;">&#160;</td>
        </tr>

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</SEC-DOCUMENT>
