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FILED AS OF DATE:		20260223
DATE AS OF CHANGE:		20260223
EFFECTIVENESS DATE:		20260223

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GeneDx Holdings Corp.
		CENTRAL INDEX KEY:			0001818331
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-HEALTH SERVICES [8000]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				851966622
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-293634
		FILM NUMBER:		26662173

	BUSINESS ADDRESS:	
		STREET 1:		333 LUDLOW STREET
		STREET 2:		NORTH TOWER, 6TH FLOOR
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06902
		BUSINESS PHONE:		888-729-1206

	MAIL ADDRESS:	
		STREET 1:		333 LUDLOW STREET
		STREET 2:		NORTH TOWER, 6TH FLOOR
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Sema4 Holdings Corp.
		DATE OF NAME CHANGE:	20210721

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CM Life Sciences, Inc.
		DATE OF NAME CHANGE:	20200715
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